- Basic information
- CohesinDB ID: CDBP00416582
- Locus: chr21-31424769-31425748
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Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, GSE67783, GSE72082, GSE98367, GSE120943, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, H1-hESC, Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 76%,
"7_Enh": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZSCAN5C, PATZ1, FOXA1, SUZ12, ZNF596, HNRNPK, ZNF362, CHD7, IKZF3, SMARCE1, TEAD1, ETV1, ZNF217, ESR1, CTCF, TCF12, BAF155, EP300, DPF2, RAD51, TEAD4, PDX1, TFAP2C, NANOG, CHD8, MYCN, CTBP1, ZNF317, ZBTB17, ZBTB48, DUX4, ERG, ONECUT1, RAD21, NKX2-1, GABPA, NKX3-1, ZNF750, CEBPB, NR3C1, GRHL2, TRPS1, ZHX2, HDAC2, GATA2, GATAD2B, SMARCA5, SMC1A, CBX1, CEBPA, SIN3A, ZFX, ZNF770, SMARCC1, PRDM10, CREBBP, ZNF384, ARNT, ZNF708, CHD1, CDK8, MED1, SCRT2, ZNF22, SP1, ASH2L, CTBP2, PHIP, BCOR, PRDM6, STAG1, FOXA2, RBBP5, HOXB13, YY1, RELA, NEUROD1, ISL1, HIF1A, GATA3, NRIP1, ZNF143, HAND2, NR2F2, TCF7L2, TP53, MYOD1, PHOX2B, AR, YAP1, ZNF324, EGLN2, SCRT1, BRD4, JUND, CLOCK, CUX1, AHR
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops