- Basic information
- CohesinDB ID: CDBP00416585
- Locus: chr21-31442329-31442578
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Data sourse: GSE25021, GSE72082, GSE86191
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Cell type: MCF-7, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 65%,
"9_Het": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, GLIS1, RUNX1, POU2F2, SMC1A, MEF2B, CEBPA, EZH2phosphoT487, EBF1, TOP2A, PAF1, ZFX, CTBP1, TEAD4, POU5F1, SMAD3, ZNF30, STAT1, FOXA1, FOXF1, ZNF770, MEF2C, HOXB13, ZNF18, ERG, RELA, ZNF35, ZNF384, ZNF341, GATA4, OSR2, ZNF184, ZFP64, ZBTB44, RAD21, ARNT, GATA3, BATF, ZNF189, SMARCE1, MAX, STAT3, NRIP1, MZF1, CDK8, MAFB, KLF4, ZNF750, CEBPB, KLF5, TEAD1, NR2F2, ZNF506, TRIM28, BCL11B, ETV1, EZH2, KMT2A, ESR1, STAT5B, ZNF573, GRHL2, ZNF334, ZNF561, CTCF, BAF155, SPI1, ZBTB20, AR, GATA6, PAX8, HDAC2, YAP1, ZNF182, ZBTB42, POU2F3, HSF1, CTBP2, PHIP, BRD4, PRDM6, ZIM3, AHR
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops