- Basic information
- CohesinDB ID: CDBP00416587
- Locus: chr21-31446580-31447006
-
Data sourse: GSE93080, GSE98367
-
Cell type: GM12878, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 52%,
"7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOXO1, SMC1A, CEBPA, ZNF263, EBF1, CDK7, RUNX1T1, MTA2, ZNF317, CDK9, ERG, KDM1A, RELA, TARDBP, NOTCH1, PBX1, MYC, PRDM1, HIF1A, GATA3, GABPA, TAL1, PAX5, ZNF143, CDK8, IKZF1, NFE2, MED1, BCL11B, MAF, STAT5B, TRIM28, MYB, KMT2A, LMO2, TP53, ZNF687, PKNOX1, MED, SETDB1, CTCF, TCF12, SP1, SPI1, TBX21, LMO1, BCL11A, INTS13, IRF4, FLI1, ASH2L, BRD4, ZNF808, TCF3, RELB, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:31075000-31100000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31200000-31225000~~chr21:31425000-31450000,
chr21:31200000-31225000~~chr21:31450000-31475000,
chr21:31325000-31350000~~chr21:31425000-31450000,
chr21:31450000-31475000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,