- Basic information
- CohesinDB ID: CDBP00416591
- Locus: chr21-31450824-31451331
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Data sourse: ENCSR000BLD, GSE67783, GSE72082, GSE86191, ENCSR000BSB, GSE138405, GSE129526, GSE25021, GSE131606
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 72%,
"5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, POU2F2, SMC1A, CHD8, TBL1X, MYCN, POU5F1, ZFX, ZSCAN16, WT1, DUX4, ZBTB48, YY1, RELA, OGG1, MYC, RAD21, SP140, GRHL3, HIF1A, NKX2-1, PRDM9, STAT3, MAX, NR3C1, TRIM28, SNAI2, EZH2, ESR1, KLF9, PHOX2B, CTCF, SPI1, AR, HEXIM1, HSF1, SCRT1, MAZ, AATF, STAG1
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:31075000-31100000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31200000-31225000~~chr21:31425000-31450000,
chr21:31200000-31225000~~chr21:31450000-31475000,
chr21:31325000-31350000~~chr21:31425000-31450000,
chr21:31450000-31475000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,