- Basic information
- CohesinDB ID: CDBP00416592
- Locus: chr21-31451655-31451855
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 77%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CEBPB, NME2, EZH2, ARNT, ZFX, SPI1
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:31075000-31100000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31200000-31225000~~chr21:31425000-31450000,
chr21:31200000-31225000~~chr21:31450000-31475000,
chr21:31325000-31350000~~chr21:31425000-31450000,
chr21:31450000-31475000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,