- Basic information
- CohesinDB ID: CDBP00416601
- Locus: chr21-31471579-31472184
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Data sourse: GSE206145-GSE177045, GSE86191
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Cell type: MCF-7, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 58%,
"5_TxWk": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, NANOG, BRD1, CHD8, MYCN, POU5F1, NKX2-2, FOXA2, ZFX, TBL1X, XBP1, ZBTB48, WT1, ZSCAN5A, SMAD3, ERG3, PRDM10, YY1, RELA, ZNF341, ATF3, MYC, CHD7, SP140, GRHL3, RAD21, ZIC2, SMC3, MAF1, PRDM14, ZFP69B, EZH2, ESR1, OCA2, GRHL2, CTCF, T, TCF12, USF1, AR, FLI1, ASH2L, NOTCH3, BCOR, E2F1, MAZ, AATF, TEAD4, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:31075000-31100000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31197655-31199851~~chr21:31476181-31477425,
chr21:31197724-31199535~~chr21:31476150-31477302,
chr21:31200000-31225000~~chr21:31450000-31475000,
chr21:31212886-31214857~~chr21:31475929-31477697,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31350000-31375000~~chr21:31475000-31500000,
chr21:31375000-31400000~~chr21:31475000-31500000,
chr21:31450000-31475000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,
chr21:31475000-31500000~~chr21:31575000-31600000,