- Basic information
- CohesinDB ID: CDBP00416602
- Locus: chr21-31472990-31473444
-
Data sourse: GSE206145-NatGen2015, GSE67783
-
Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 65%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: GLIS1, CHD8, ZSCAN5D, NKX2-2, ZFX, ZNF600, MAFF, DDX5, PRDM10, RELA, ZNF384, ASCL1, NEUROD1, RFX1, ZIC2, OTX2, NKX2-1, PRDM9, STAT3, MITF, HNRNPH1, CEBPB, TRIM28, C11orf30, ZNF334, SETDB1, PHOX2B, CTCF, ZNF577, MAFK, SPI1, AR, GATA6, ZNF479, ZNF644, ZNF766, ZNF316
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:31075000-31100000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31197655-31199851~~chr21:31476181-31477425,
chr21:31197724-31199535~~chr21:31476150-31477302,
chr21:31200000-31225000~~chr21:31450000-31475000,
chr21:31212886-31214857~~chr21:31475929-31477697,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31350000-31375000~~chr21:31475000-31500000,
chr21:31375000-31400000~~chr21:31475000-31500000,
chr21:31450000-31475000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,
chr21:31475000-31500000~~chr21:31575000-31600000,