- Basic information
- CohesinDB ID: CDBP00416604
- Locus: chr21-31476481-31476950
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Data sourse: ENCSR000BLD, ENCSR000BTQ, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE138405, GSE129526, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, ENCSR000ECE, ENCSR000EHX, GSE121355, GSE68388, ENCSR703TNG, GSE25021, GSE116344, ENCSR917QNE
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, Hela-Kyoto, RH4, SK-N-SH, Liver, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 65%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, SMC1A, FOXA2, NKX2-2, CEBPA, MEIS1, SOX2, ZFX, ZNF716, ZSCAN16, DUX4, KDM4B, FOXA1, SRF, ZNF563, DDX5, HOXB13, YY1, RELA, AHR, BMI1, RFX1, ZNF184, RAD21, ARNT, OTX2, ZNF189, MAFB, NKX3-1, ZNF667, ARNTL, STAT5B, TERF1, SCRT2, EZH2, STAG1, TP53, PKNOX1, ESR1, KDM5B, SETDB1, CTCF, BCL11A, AR, GATA2, ZNF674, HOXA9, PRDM6, ZIM3, PDX1, ZNF316
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31450000-31475000,
chr21:31075000-31100000~~chr21:31450000-31475000,
chr21:31175000-31200000~~chr21:31450000-31475000,
chr21:31197655-31199851~~chr21:31476181-31477425,
chr21:31197724-31199535~~chr21:31476150-31477302,
chr21:31200000-31225000~~chr21:31450000-31475000,
chr21:31212886-31214857~~chr21:31475929-31477697,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31350000-31375000~~chr21:31475000-31500000,
chr21:31375000-31400000~~chr21:31475000-31500000,
chr21:31450000-31475000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,
chr21:31475000-31500000~~chr21:31575000-31600000,