- Basic information
- CohesinDB ID: CDBP00416611
- Locus: chr21-31492179-31493117
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Data sourse: GSE206145, GSE206145-GSE177045, GSE120943, GSE98367
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Cell type: MCF-7, Macrophage, Monocytes, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,NIPBL,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 78%,
"5_TxWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, ZSCAN5C, NME2, XBP1, FOXA1, PBX2, PRDM1, DPF1, ZSCAN4, ELF1, SAP30, ESR1, OCA2, USF2, CTCF, TCF12, E4F1, RAD51, ZNF528, KLF3, TEAD4, EHMT2, NANOG, POU2F2, ZSCAN5D, TOP2A, ZNF317, ZBTB17, DUX4, ZSCAN5A, ZBTB48, ZNF485, TBP, ASCL1, ZNF341, MYC, TRIP13, SMARCA4, GRHL3, GABPA, STAT3, NKX3-1, CEBPB, EZH2, FEZF1, GABPB1, ELF4, SPI1, SIX2, FLI1, NFYB, CBX1, NKX2-2, ZFX, ZNF18, CREBBP, NFYC, OSR2, ZEB2, NFYA, SP2, FOS, NR2C1, MED1, ZXDB, ZNF558, L3MBTL2, USF1, REST, RBM25, PHIP, PRDM6, SMC3, CBFA2T2, CBX3, FOXA2, TBL1X, ZNF600, ZNF692, ZSCAN16, WT1, RELA, NEUROD1, HIF1A, GATA3, TAL1, MAX, ZNF143, HAND2, PLAG1, NCOA3, PKNOX1, ZNF334, MYOD1, EGR2, PHOX2B, BRD2, AR, ZBTB40, ZNF324, ZNF366, HSF1, BRD4, SCRT1, MAZ
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops