- Basic information
- CohesinDB ID: CDBP00416614
- Locus: chr21-31498303-31499593
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE131606, GSE25021, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, GSE67783, GSE86191, GSE138405, GSE76893, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE129526, GSE68388, GSE83726, GSE50893
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Cell type: RH4, GM10847, GM2610, CVB-hiPSC, GM19240, HSPC, HuCC-T1, H9-hESC, GM2630, Ishikawa, GM12890, GM2255, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19099, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, GM19238, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 19% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.611
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
59% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 74%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, CHD8, FOXA2, NKX2-2, ZSCAN5D, MEIS1, MYCN, ZFX, ZNF600, XBP1, ZBTB17, DUX4, ZBTB48, ZSCAN5A, FOXA1, POU4F2, ZNF574, SP4, TWIST1, TBP, YY1, RELA, ZNF35, ASCL1, NEUROD1, ATF3, MYC, ZNF341, SMARCA4, OSR2, ATF4, OTX2, ZNF189, MAX, NKX3-1, GATA1, ZNF143, MITF, MED1, NR3C1, CEBPB, TRIM28, ZNF573, FOXK1, EZH2, OCA2, TP73, MED26, MED, ZNF334, GRHL2, EBF3, MYOD1, BCL6B, BRD2, ZNF507, USF1, CTCF, AR, KLF17, GATA2, ZBTB42, RAD51, MXI1, SCRT1, BRD4, TCF3, TEAD4, TFAP2C
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31500000-31525000,
chr21:31175000-31200000~~chr21:31500000-31525000,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31250000-31275000~~chr21:31500000-31525000,
chr21:31325000-31350000~~chr21:31500000-31525000,
chr21:31350000-31375000~~chr21:31475000-31500000,
chr21:31350000-31375000~~chr21:31500000-31525000,
chr21:31375000-31400000~~chr21:31475000-31500000,
chr21:31375000-31400000~~chr21:31500000-31525000,
chr21:31475000-31500000~~chr21:31575000-31600000,
chr21:31498536-31499888~~chr21:31579669-31582192,
chr21:31498536-31499888~~chr21:31603531-31606025,
chr21:31498552-31499739~~chr21:31580295-31581613,
chr21:31498554-31500056~~chr21:31579918-31582232,