- Basic information
- CohesinDB ID: CDBP00416615
- Locus: chr21-31501580-31502477
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Data sourse: GSE206145-GSE177045, GSE72082, GSE129526, GSE206145-NatGen2015, GSE68388, ENCSR703TNG
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Cell type: MCF-7, Fibroblast, HCT-116, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 65%,
"5_TxWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, FOXA1, ATF3, NFIC, SMARCE1, PAX5, ZNF467, TEAD1, KLF6, SNAI2, LMO2, ESR1, ZNF217, CTCF, BAF155, EP300, DPF2, SMC1, TEAD4, TFAP2C, GLIS1, NANOG, CHD8, ZSCAN5D, POU5F1, ZNF263, CTBP1, ZBTB48, ZNF205, DDX5, ARID3A, HNF4G, ERG, RAD21, GRHL3, STAT3, NKX3-1, RCOR1, DNMT3B, NR3C1, CEBPB, ESRRA, ZNF750, EZH2, GRHL2, ZNF652, HDAC2, GATA2, SMC1A, SIN3A, ZFX, SMAD3, ZNF654, ZNF18, ZBTB2, ZNF384, PBX4, SNIP1, FOS, TEAD3, SMAD1, SP1, HNF4A, ZNF479, CTBP2, SMC3, STAG1, ZNF283, FOXA2, EBF1, MIER2, WT1, HOXB13, KDM1A, YY1, RELA, GATA3, MAX, MTA1, KLF4, NR2F2, TCF7L2, KDM5B, ZNF334, ELF3, HSF1, BRD4, MAZ, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31500000-31525000,
chr21:31175000-31200000~~chr21:31500000-31525000,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31250000-31275000~~chr21:31500000-31525000,
chr21:31325000-31350000~~chr21:31500000-31525000,
chr21:31350000-31375000~~chr21:31475000-31500000,
chr21:31350000-31375000~~chr21:31500000-31525000,
chr21:31375000-31400000~~chr21:31475000-31500000,
chr21:31375000-31400000~~chr21:31500000-31525000,
chr21:31475000-31500000~~chr21:31575000-31600000,
chr21:31498536-31499888~~chr21:31579669-31582192,
chr21:31498536-31499888~~chr21:31603531-31606025,
chr21:31498552-31499739~~chr21:31580295-31581613,
chr21:31498554-31500056~~chr21:31579918-31582232,