- Basic information
- CohesinDB ID: CDBP00416616
- Locus: chr21-31504028-31504384
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Data sourse: GSE101921, GSE111913
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Cell type: RT-112, HMEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 64%,
"5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, FOXO1, PGR, MEIS2, XBP1, PATZ1, FOXA1, PBX2, ZFHX2, HNRNPK, HDGF, ZNF362, CHD7, PRDM1, RUNX3, ZNF189, PAX5, TP63, ZSCAN4, ZNF467, ZNF629, KLF5, TEAD1, ELF1, TRIM28, ZNF217, ESR1, ZNF624, TP73, OCA2, CTCF, TCF12, EP300, DPF2, IRF4, ZNF423, SMC1, TEAD4, PDX1, TFAP2C, NANOG, POU2F2, POU5F1, MYCN, MTA2, ZBTB17, ZNF317, ZSCAN5A, SRF, DDX5, NBN, ERG2, ARID3A, ERG, ZBTB8A, MYC, GRHL3, GABPA, IKZF1, RCOR1, ZNF639, ZNF750, CEBPB, NR3C1, KMT2A, EZH2, GRHL2, SPI1, KLF17, IRF1, PCBP1, HDAC2, SIX2, FLI1, RELB, NCOA2, ZNF585A, SMC1A, BCL6, CEBPA, SIN3A, ZFX, PCBP2, ERG3, TRIM22, ZNF18, MEF2A, CREBBP, ZNF384, ZNF35, OSR2, ARNT, ATF2, PBX3, CBFA2T3, MED1, MYB, ZNF680, ZNF22, SP1, BCL11A, ATF7, POU2F3, ASH2L, ZNF605, CTBP2, PHIP, BCOR, FOXP1, NCOR2, MLLT1, STAG2, NFATC3, MEF2B, ZNF207, EBF1, CHD2, E2F8, ZNF600, WT1, ZNF662, MEF2C, CDK9, KDM1A, YY1, RELA, TARDBP, ZIC2, HIF1A, SKIL, ZFP36, GATA3, BATF, TAL1, MAX, NRIP1, ZNF143, TLE3, KLF4, CEBPG, SP7, NR2F2, NR2F1, ZNF687, PKNOX1, ZNF645, ZNF140, EGR2, T, TBX21, BHLHE40, AR, ZBTB40, ZNF324, NOTCH3, IKZF2, BRD4, ZSCAN23
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:27500000-27525000~~chr21:31500000-31525000,
chr21:31175000-31200000~~chr21:31500000-31525000,
chr21:31197748-31199515~~chr21:31508678-31510577,
chr21:31250000-31275000~~chr21:31475000-31500000,
chr21:31250000-31275000~~chr21:31500000-31525000,
chr21:31325000-31350000~~chr21:31500000-31525000,
chr21:31346852-31348335~~chr21:31508604-31510568,
chr21:31350000-31375000~~chr21:31475000-31500000,
chr21:31350000-31375000~~chr21:31500000-31525000,
chr21:31375000-31400000~~chr21:31475000-31500000,
chr21:31375000-31400000~~chr21:31500000-31525000,
chr21:31475000-31500000~~chr21:31575000-31600000,
chr21:31498536-31499888~~chr21:31579669-31582192,
chr21:31498536-31499888~~chr21:31603531-31606025,
chr21:31498552-31499739~~chr21:31580295-31581613,
chr21:31498554-31500056~~chr21:31579918-31582232,