- Basic information
- CohesinDB ID: CDBP00416627
- Locus: chr21-31521721-31522259
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Data sourse: GSE67783, GSE86191, GSE98367, GSE206145, GSE120943
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Cell type: RPE, HCT-116, Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 74%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: E2F7, ZSCAN5C, PATZ1, FOXA1, ZFP64, ZBTB44, PRDM1, CHD7, IKZF3, ZNF189, MZF1, ZSCAN4, ZNF736, ZNF467, MYOG, ZNF121, ETV1, KLF10, PITX3, ZNF561, CTCF, ZBTB20, PRDM4, ZNF528, RBPJ, GLIS1, POU2F2, MYCN, ZNF317, ZBTB17, ZBTB48, ZSCAN5A, DDX5, ERG2, ERG, ASCL1, ZBTB8A, MYC, ZNF671, TSHZ1, RCOR1, FOXK1, EZH2, KLF8, FEZF1, ZNF664, ZNF182, SIX2, MYF5, ZBTB12, ERG3, ZNF18, PRDM10, SMARCC1, ZNF792, ZNF35, OSR2, ZNF184, ZEB2, ZNF10, MED1, ZXDB, SCRT2, PHIP, PRDM6, ZNF34, ZNF283, ZNF600, ZSCAN16, ZNF692, WT1, ZNF30, FOXF1, HOXB13, KDM1A, ZIC2, HIF1A, MAX, HAND2, TP53, PKNOX1, ZBTB6, MYOD1, EGR2, BRD2, AR, PAX3-FOXO1, ZBTB42, ZNF366, ZBTB26, SCRT1, BRD4
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops