- Basic information
- CohesinDB ID: CDBP00416631
- Locus: chr21-31527262-31532342
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, GSE72082, ENCSR000BLY, GSE105028, GSE121355, GSE25021, GSE131606, GSE115602, GSE93080, GSE67783, GSE86191, GSE76893, GSE206145-NatGen2015, ENCSR703TNG, ENCSR000BLS, ENCSR000EHW, GSE206145, ENCSR000EHX, ENCSR000BTQ, GSE110061, GSE129526, GSE111913
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, HCT-116, HEK293T, Hep-G2, GM12878, DKO, SK-N-SH, RT-112, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.856
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 39%,
"7_Enh": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXA2, NKX2-2, RBBP5, ZNF263, PAF1, ZFX, MYCN, FOXA1, ZNF770, ERG, ONECUT1, GATA4, GATA3, ETV1, ESR1, MYOD1, BRD2, BCL11A, AR, GATA6, HDAC2, BRD4, PHIP, FOXP1, MAZ, PDX1
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 52
- Number of somatic mutations (non-coding): 0
- Related genes and loops