- Basic information
- CohesinDB ID: CDBP00416638
- Locus: chr21-31543154-31543927
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Data sourse: GSE116868, ENCSR000HPG, GSE97394
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Cell type: IMR-90, MB157, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 52%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, CBFA2T2, CHD8, PGR, TBL1X, ZFX, ZNF600, XBP1, ZBTB48, WT1, STAT1, SMAD3, FOXF1, TET2, FOXA1, SUZ12, PRDM10, ERG, YY1, RELA, RUNX2, MYC, OSR2, RAD21, NRF1, HIF1A, ARNT, CBFB, SMC3, STAT3, MZF1, FOS, NR3C1, ZNF629, CEBPB, ZNF558, ZBTB11, NR2F1, NFE2L2, EZH2, TFAP2C, ESR1, TP53, MED26, BMPR1A, TP73, FEZF1, GRHL2, ZNF561, ZNF334, BRD2, CTCF, GSPT2, BHLHE40, AR, EGLN2, HSF1, BRD4, PHIP, E2F1, MAZ, PRDM6, ZIM3, RBPJ
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 0
- Related genes and loops