- Basic information
- CohesinDB ID: CDBP00416639
- Locus: chr21-31544344-31545497
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE67783, GSE86191, GSE72082, ENCSR703TNG
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Cell type: MCF-7, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CBX1, NANOG, ZSCAN5D, MYCN, POU5F1, ZBTB24, SIN3A, SOX2, CTBP1, TOP2A, GTF2B, FOXA1, RELA, CREBBP, ZNF384, NEUROD1, ZNF362, CHD7, ARNT, OTX2, GATA3, ATF2, ZNF189, STAT3, MAX, NRIP1, RCOR1, HAND2, TLE3, ZNF750, NR2F2, TEAD1, TRIM28, TFAP2C, NR2F1, CREB1, TCF7L2, ESR1, ZNF687, GRHL2, EBF3, TRPS1, PHOX2B, JUN, EP300, TFAP2A, MNT, AR, DPF2, HDAC2, GATA2, YAP1, GATAD2B, BRD4, CTBP2, MBD2, PHIP, CUX1, TEAD4, TBX2, AHR
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops