- Basic information
- CohesinDB ID: CDBP00416641
- Locus: chr21-31548490-31549150
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BSB, ENCSR000BLY, GSE105028, GSE121355, GSE131606, GSE25021, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE67783, GSE86191, GSE138405, ENCSR703TNG, GSE106870, GSE145327, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE110061, GSE129526, ENCSR000EDE, GSE68388, GSE126990, GSE50893
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Cell type: GM10847, GM2610, CVB-hiPSC, GM19240, HSPC, CVI-hiPSC, HuCC-T1, H9-hESC, GM2630, GM12890, HeLa-S3, GM2255, GM18486, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19099, HUES64, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, GM19238, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 16% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.644
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, CHD8, SMC1A, FOXA2, PGR, SOX2, ZFX, ZNF600, ZNF692, ZBTB17, DUX4, WT1, PATZ1, FOXA1, XBP1, ZNF574, ZNF770, DDX5, HOXB13, TWIST1, PRDM10, TBP, ERG, SMARCC1, RELA, ZNF35, ZNF384, ZBTB2, ZBTB8A, ZNF341, MYC, YY1, ZFP64, OSR2, GATA4, ZBTB44, ZNF362, IKZF3, HIF1A, RFX1, RAD21, ZNF184, SP140, SMC3, GABPA, STAT3, MAX, ZNF736, ZNF467, TLE3, CEBPB, KLF5, TEAD1, TRIM28, ZNF121, SCRT2, PIAS1, EZH2, LMO2, TP53, ZBTB6, ESR1, ZNF334, PHOX2B, BRD2, CTCF, BAF155, ZNF695, AR, GATA2, ZNF324, PRDM4, ZBTB42, FLI1, SCRT1, PHIP, BRD4, FOXP1, CUX1, PRDM6, MAZ, ZNF528, SMC1, STAG1
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 0
- Related genes and loops