- Basic information
- CohesinDB ID: CDBP00416648
- Locus: chr21-31564328-31564817
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE104888
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Cell type: RPE, Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 56%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, CBX3, ZNF600, ZSCAN16, SMAD3, SUZ12, ERG, ZNF384, ATF3, CTCFL, ZNF184, GATA3, PBX3, FOS, CDK8, VDR, ZNF22, JUN, TCF12, BRD2, SIX2, BRD4, ZNF554, FOSL2
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:31175000-31200000~~chr21:31550000-31575000,
chr21:31197589-31199959~~chr21:31565573-31567413,
chr21:31197748-31199515~~chr21:31565524-31567074,
chr21:31197753-31199935~~chr21:31565273-31566860,
chr21:31200000-31225000~~chr21:31550000-31575000,
chr21:31325000-31350000~~chr21:31550000-31575000,
chr21:31343102-31344948~~chr21:31557869-31560689,
chr21:31346686-31348373~~chr21:31565575-31566814,
chr21:31346706-31348459~~chr21:31565524-31567074,
chr21:31350000-31375000~~chr21:31550000-31575000,
chr21:31450000-31475000~~chr21:31550000-31575000,