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Basic information

CohesinDB ID: CDBP00416655

Locus: chr21-31588397-31588660

Data sourse: GSE206145-NatGen2015, GSE67783

Cell type: Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 82%, "14_ReprPCWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, ZSCAN5D, ZSCAN5C, ZNF778, CRY1, ZFX, CTBP1, ZNF600, TEAD4, WT1, ZSCAN5A, ZBTB48, FOXA1, NME2, ZNF770, MAFF, DDX5, SP4, ZNF580, ZNF18, HOXB13, HNRNPK, YY1, RELA, CREBBP, ZNF35, ZBTB8A, ZNF362, OSR2, ZNF610, ARNT, IKZF3, HIF1A, ATF2, ZEB2, ZSCAN4, ZNF449, ZNF143, ZNF320, ZNF467, ZNF629, SP7, KLF5, ZNF264, FOXK1, KLF10, ZNF624, PKNOX1, OCA2, FEZF1, ZNF561, EGR2, CTCF, ZNF843, MAFK, KLF1, GSPT2, KLF17, PRDM4, ZBTB42, ZNF423, PHIP, ZNF528, PRDM6, KLF3, ZNF554, ZNF316

Target gene symbol (double-evidenced CRMs): TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416655