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Basic information

CohesinDB ID: CDBP00416658

Locus: chr21-31596869-31598169

Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, GSE131606

Cell type: RPE, Fibroblast, HCT-116, HSPC, DKO

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 61%, "14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PBX1, MYC, ZSCAN5D, TRIM28, ZNF610, EZH2, ZFX, NOTCH3, WT1, TCF3, MAZ, MAX, CTCF, SPI1

Target gene symbol (double-evidenced CRMs): TIAM1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 14

Related genes and loops

Related gene: ENSG00000156299,

eachgene

Deatailed information for cohesin site CDBP00416658