- Basic information
- CohesinDB ID: CDBP00416659
- Locus: chr21-31598709-31599354
-
Data sourse: GSE50893, GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, HCT-116, GM18951, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 71%,
"14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, GLIS1, TRP47, SMC1A, ZNF263, MYCN, CRY1, ZFX, ZNF600, XBP1, NME2, ZBTB48, WT1, TET2, ZNF770, ERG3, ERG2, PBX2, ZFHX2, ERG, YY1, RELA, OGG1, OSR2, SP140, ARNT, NRF1, HIF1A, GRHL3, ATF4, ZNF189, XRCC5, TERF1, ZNF121, ZNF558, ZNF680, EZH2, KDM5B, OCA2, ZBTB6, PKNOX1, ZNF334, MYOD1, EGR2, CTCF, T, HNF4A, AR, GATA6, RXR, REST, ZNF479, EGLN2, ZNF366, HEXIM1, E2F4, RNF2, NOTCH3, ZNF528, AATF, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000156299,
- Related loop:
chr21:29075000-29100000~~chr21:31600000-31625000,
chr21:30025000-30050000~~chr21:31600000-31625000,
chr21:30050000-30075000~~chr21:31575000-31600000,
chr21:30050000-30075000~~chr21:31600000-31625000,
chr21:30325000-30350000~~chr21:31600000-31625000,
chr21:30425000-30450000~~chr21:31600000-31625000,
chr21:30825000-30850000~~chr21:31600000-31625000,
chr21:30830642-30832041~~chr21:31603800-31605717,
chr21:30830671-30832343~~chr21:31603478-31605998,
chr21:30838921-30840264~~chr21:31603607-31605876,
chr21:30875000-30900000~~chr21:31600000-31625000,
chr21:30950000-30975000~~chr21:31600000-31625000,
chr21:31075000-31100000~~chr21:31575000-31600000,
chr21:31075000-31100000~~chr21:31600000-31625000,
chr21:31097524-31100200~~chr21:31603561-31606243,
chr21:31097635-31100206~~chr21:31603602-31605948,
chr21:31097659-31100122~~chr21:31603531-31606025,
chr21:31097662-31099856~~chr21:31603619-31605810,
chr21:31097665-31099883~~chr21:31603773-31605883,
chr21:31097685-31100223~~chr21:31603435-31606015,
chr21:31097693-31099837~~chr21:31603761-31605998,
chr21:31097698-31099915~~chr21:31603571-31605761,
chr21:31097703-31099820~~chr21:31603740-31605904,
chr21:31097825-31099965~~chr21:31604036-31605562,
chr21:31097828-31099837~~chr21:31603469-31605983,
chr21:31097834-31100105~~chr21:31603560-31606026,
chr21:31097840-31099933~~chr21:31604013-31605728,
chr21:31097840-31099938~~chr21:31603779-31605751,
chr21:31097847-31099741~~chr21:31603808-31605732,
chr21:31097852-31099834~~chr21:31603977-31605609,
chr21:31097852-31100234~~chr21:31603563-31605907,
chr21:31097866-31100218~~chr21:31603484-31605864,
chr21:31097869-31099852~~chr21:31603478-31605998,
chr21:31097870-31099669~~chr21:31603921-31605829,
chr21:31097873-31099839~~chr21:31603801-31605813,
chr21:31097877-31099898~~chr21:31603659-31605983,
chr21:31097883-31100039~~chr21:31603595-31606017,
chr21:31097887-31099865~~chr21:31603607-31605876,
chr21:31097887-31099866~~chr21:31603648-31605747,
chr21:31097893-31100303~~chr21:31603591-31605976,
chr21:31097894-31099945~~chr21:31603826-31605735,
chr21:31097896-31099782~~chr21:31603800-31605717,
chr21:31097903-31099685~~chr21:31603616-31605759,
chr21:31097906-31099678~~chr21:31603705-31605771,
chr21:31097906-31100239~~chr21:31603767-31606045,
chr21:31097923-31099913~~chr21:31603790-31605769,
chr21:31097936-31099894~~chr21:31603758-31605876,
chr21:31097941-31100177~~chr21:31603985-31605548,
chr21:31097943-31100132~~chr21:31604008-31605560,
chr21:31098003-31099384~~chr21:31604127-31605513,
chr21:31098023-31099887~~chr21:31604024-31605520,
chr21:31100000-31125000~~chr21:31575000-31600000,
chr21:31100000-31125000~~chr21:31600000-31625000,
chr21:31108225-31109947~~chr21:31603740-31605904,
chr21:31108247-31110001~~chr21:31603560-31606026,
chr21:31108302-31109934~~chr21:31603591-31605976,
chr21:31108349-31109945~~chr21:31603460-31605984,
chr21:31108376-31109926~~chr21:31603651-31605924,
chr21:31108420-31109889~~chr21:31603648-31605747,
chr21:31125000-31150000~~chr21:31575000-31600000,
chr21:31150000-31175000~~chr21:31575000-31600000,
chr21:31175000-31200000~~chr21:31575000-31600000,
chr21:31175000-31200000~~chr21:31600000-31625000,
chr21:31179704-31181750~~chr21:31603484-31605864,
chr21:31179749-31181978~~chr21:31603531-31606025,
chr21:31179770-31181885~~chr21:31603563-31605907,
chr21:31197237-31199506~~chr21:31603761-31605998,
chr21:31197303-31199956~~chr21:31603460-31605984,
chr21:31197589-31199959~~chr21:31603435-31606015,
chr21:31197601-31199886~~chr21:31603659-31605983,
chr21:31197619-31199531~~chr21:31603560-31606026,
chr21:31197637-31199884~~chr21:31603484-31605864,
chr21:31197648-31199955~~chr21:31603571-31605761,
chr21:31197650-31199906~~chr21:31603651-31605924,
chr21:31197654-31199860~~chr21:31603573-31605798,
chr21:31197655-31199851~~chr21:31603531-31606025,
chr21:31197672-31199906~~chr21:31603773-31605883,
chr21:31197678-31199846~~chr21:31603607-31605876,
chr21:31197682-31199946~~chr21:31603563-31605907,
chr21:31197714-31199904~~chr21:31603602-31605948,
chr21:31197715-31199809~~chr21:31603496-31605683,
chr21:31197719-31199532~~chr21:31603914-31605899,
chr21:31197724-31199535~~chr21:31603800-31605717,
chr21:31197729-31199566~~chr21:31603591-31605976,
chr21:31197736-31199514~~chr21:31603767-31606045,
chr21:31197737-31199840~~chr21:31603478-31605998,
chr21:31197748-31199515~~chr21:31603808-31605732,
chr21:31197752-31199500~~chr21:31603826-31605735,
chr21:31197753-31199935~~chr21:31603595-31606017,
chr21:31197755-31199442~~chr21:31603818-31605771,
chr21:31197756-31199452~~chr21:31603885-31605723,
chr21:31197757-31199878~~chr21:31603790-31605769,
chr21:31197757-31199907~~chr21:31603705-31605771,
chr21:31197763-31199891~~chr21:31603469-31605983,
chr21:31197765-31199962~~chr21:31603561-31606243,
chr21:31197780-31199473~~chr21:31603619-31605810,
chr21:31197780-31199925~~chr21:31603801-31605813,
chr21:31197787-31199879~~chr21:31603591-31605843,
chr21:31197801-31199880~~chr21:31604008-31605560,
chr21:31197807-31199502~~chr21:31604014-31605561,
chr21:31197808-31199851~~chr21:31603762-31606023,
chr21:31197818-31199455~~chr21:31603899-31605786,
chr21:31197883-31199835~~chr21:31604013-31605728,
chr21:31197888-31199879~~chr21:31603985-31605548,
chr21:31197890-31199733~~chr21:31604000-31605577,
chr21:31197901-31199794~~chr21:31603977-31605609,
chr21:31197910-31199531~~chr21:31603902-31605637,
chr21:31197925-31199613~~chr21:31604024-31605520,
chr21:31197954-31199538~~chr21:31604063-31605499,
chr21:31198011-31199951~~chr21:31603779-31605751,
chr21:31198078-31199477~~chr21:31603567-31605676,
chr21:31200000-31225000~~chr21:31575000-31600000,
chr21:31200000-31225000~~chr21:31600000-31625000,
chr21:31212839-31214885~~chr21:31603602-31605948,
chr21:31213183-31214841~~chr21:31603798-31605786,
chr21:31213256-31214845~~chr21:31603469-31605983,
chr21:31213437-31214794~~chr21:31603705-31605771,
chr21:31213444-31214691~~chr21:31603818-31605771,
chr21:31225000-31250000~~chr21:31575000-31600000,
chr21:31250000-31275000~~chr21:31575000-31600000,
chr21:31250000-31275000~~chr21:31600000-31625000,
chr21:31300000-31325000~~chr21:31575000-31600000,
chr21:31325000-31350000~~chr21:31575000-31600000,
chr21:31325000-31350000~~chr21:31600000-31625000,
chr21:31346790-31348380~~chr21:31604014-31605561,
chr21:31375000-31400000~~chr21:31575000-31600000,
chr21:31400000-31425000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31575000-31600000,
chr21:31450000-31475000~~chr21:31600000-31625000,
chr21:31475000-31500000~~chr21:31575000-31600000,
chr21:31498536-31499888~~chr21:31603531-31606025,
chr21:31600000-31625000~~chr21:31950000-31975000,