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Basic information

CohesinDB ID: CDBP00416664

Locus: chr21-31612718-31614026

Data sourse: GSE138405, GSE67783, GSE86191, GSE206145

Cell type: RPE, Hela-Kyoto, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SMC3ac,Rad21,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 52%, "14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, CHD8, SMC1A, MYCN, MEIS1, SOX2, ZFX, POU4F2, ZNF317, RUNX1T1, WT1, ZNF534, ZSCAN5A, FOXA1, ERG3, ERG2, ZNF28, ZFHX2, ERG, KDM1A, RELA, PBX1, ASCL1, USP7, ATF3, ZFP64, MCM3, CHD7, GRHL3, DAXX, HIF1A, NKX2-1, OTX2, GATA3, MAF1, TAL1, FOS, CDK8, MITF, KLF4, ESRRA, TRIM28, KMT2A, TCF7L2, EZH2, LMO2, TP53, MED, ZNF334, EGR2, CTCF, BCL11A, SPI1, ZBTB20, AR, ZBTB16, RXR, FLI1, NOTCH3, BRD4, EED, TCF3, MAZ, SMC3, STAG1, TFAP2C, FOSL2

Target gene symbol (double-evidenced CRMs): TIAM1,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000156299, ENSG00000142149,

eachgene

Deatailed information for cohesin site CDBP00416664