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Basic information

CohesinDB ID: CDBP00416670

Locus: chr21-31629809-31630668

Data sourse: ENCSR853VWZ, GSE131606, GSE104888, ENCSR230ZWH, GSE72082, GSE86191, ENCSR000BSB, GSE138405, GSE116344, GSE129526, GSE206145-GSE177045, ENCSR000BLY, GSE206145, ENCSR000EDE, GSE68388, ENCSR703TNG, GSE126990, GSE108869, ENCSR000ECS, ENCSR917QNE

Cell type: MCF-7, RPE, Hela-Kyoto, HCT-116, RH4, A-549, HeLa-S3, SK-N-SH, Liver, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.889

Subunit: NIPBL,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 77%, "7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, SMARCA2, ZNF660, XBP1, HNF1A, PATZ1, FOXA1, ATF3, NFIC, ZFP64, ZNF362, ZBTB44, CHD7, PRDM1, ZNF189, SMARCE1, TP63, ZNF629, TEAD1, ELF1, KLF6, SNAI2, ZNF217, ESR1, OCA2, HNF1B, CTCF, TCF12, JUN, BAF155, EP300, DPF2, RFX5, E2F1, ZNF528, TEAD4, GTF2F1, PDX1, POU2F2, BRD3, ZSCAN21, ZBTB17, ZBTB48, ERG2, HIC1, TBP, HOXC5, ZBTB21, ERG, EZH1, MYC, SMARCA4, HOMEZ, RAD21, LHX2, GRHL3, RXRA, NKX2-1, GABPA, STAT3, APC, NKX3-1, RCOR1, ZNF639, ARNTL, NR3C1, ESRRA, CEBPB, CREB1, KLF8, FEZF1, GRHL2, IRF1, GATA2, FLI1, SMARCA5, MRTFB, ZNF554, SMC1A, CBX1, NKX2-2, AFF4, ZFX, ZNF335, SIN3A, SMAD3, TWIST1, PRDM10, SMARCC1, CREBBP, ZNF35, RUNX2, ZNF184, ARNT, PBX4, DAXX, NFIB, ZNF518A, ZEB2, PBX3, MAFB, FOS, CDK8, ZXDB, SCRT2, PIAS1, NR1H2, TBX5, MAFK, SP1, BCL11A, HNF4A, REST, ARID1A, ZHX1, ASH2L, PHIP, FOXP1, PRDM6, ZNF394, PPARG, TBL1X, FOXA2, CHD2, ZNF600, ZNF692, ZSCAN16, ZNF30, MAFF, ZNF574, ZBTB33, HOXB13, YY1, RELA, JUNB, NEUROD1, MCM3, OTX2, GATA3, TAL1, MAX, NRIP1, ZNF143, CBX2, TLE3, KLF4, SP7, NCOA3, NR2F2, TCF7L2, NR2F1, TP53, NFKB1, PHOX2B, ELF3, BRD2, AR, ZNF579, ZNF324, ZNF366, RNF2, NOTCH3, BRD4, JUND, SCRT1, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00416670