- Basic information
- CohesinDB ID: CDBP00416674
- Locus: chr21-31644709-31645878
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Data sourse: GSE206145, GSE101921, GSE206145-NatGen2015, GSE86191
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Cell type: RPE, Fibroblast, HCT-116, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 84%,
"7_Enh": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, PPARG, BRD3, MEIS1, ZFX, CTBP1, ZBTB48, STAT1, FOXA1, ERG3, DDX5, HOXB13, PRDM10, ERG, YY1, RELA, HDGF, ZNF35, LYL1, JUNB, ETS1, MYC, ZNF148, GATA4, SP140, PRDM1, ARNT, GABPA, ZEB2, TAL1, SMARCE1, STAT3, XRCC5, HMBOX1, IKZF1, CDK8, CDX2, CEBPB, ZNF592, PIAS1, LMO2, OCA2, L3MBTL2, BRD2, CTCF, SPI1, E4F1, BAF155, HNF4A, AR, GATA6, DPF2, ZBTB40, GATA2, TRIM24, ASH2L, NCOR1, SMC1, SMC3, NCOR2, ZNF24, STAG2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops