- Basic information
- CohesinDB ID: CDBP00416696
- Locus: chr21-31695434-31696225
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Data sourse: GSE138405, GSE62063
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Cell type: Hela-Kyoto, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SMC3ac
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 73%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX3, PAF1, SOX2, GTF2B, ZBTB12, FOXA1, LEO1, HOXB13, ZNF18, CREB3L1, HOXC5, RELA, ERG, ZNF384, CHAMP1, OSR2, HOMEZ, GRHL3, ATF2, PRDM9, GLYR1, TAL1, SUPT5H, AGO2, ZNF334, JUN, RBM22, CTCF, SPI1, ELF3, ZNF664, SIX2, ZNF777, BRD4, ZZZ3
- Target gene symbol (double-evidenced CRMs): SYNJ1,SCAF4,PAXBP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 78
- Number of somatic mutations (non-coding): 26
- Related genes and loops
- Related gene:
ENSG00000156304,
ENSG00000159082,
ENSG00000159086,
- Related loop:
chr21:29025000-29050000~~chr21:31675000-31700000,
chr21:29050000-29075000~~chr21:31675000-31700000,
chr21:31250000-31275000~~chr21:31700000-31725000,
chr21:31375000-31400000~~chr21:31700000-31725000,
chr21:31675000-31700000~~chr21:32725000-32750000,
chr21:31675000-31700000~~chr21:32750000-32775000,
chr21:31675000-31700000~~chr21:39175000-39200000,
chr21:31700000-31725000~~chr21:32600000-32625000,