- Basic information
- CohesinDB ID: CDBP00416701
- Locus: chr21-31710228-31711264
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Data sourse: ENCSR230ZWH, GSE67783, GSE138405, ENCSR917QNE, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE165895
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Cell type: RPE, Hela-Kyoto, Fibroblast, K-562, Liver, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3ac
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 53%,
"7_Enh": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TOP2A, PAF1, ZNF600, ZSCAN16, ZBTB48, ERG3, PRDM10, YY1, ZNF384, NEUROD1, MYC, PRDM1, ARNT, NKX2-1, GATA3, OTX2, ZEB2, ZNF383, SUPT5H, IKZF1, FEZF1, BRD2, RBM22, SPI1, HNF4A, TAF1, PHIP
- Target gene symbol (double-evidenced CRMs): TIAM1,CFAP298-TCP10L,SCAF4,SYNJ1,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 5
- Related genes and loops