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Basic information

CohesinDB ID: CDBP00416708

Locus: chr21-31720387-31721045

Data sourse: GSE206145-GSE177045, ENCSR000FAD

Cell type: K-562, MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 55%, "15_Quies": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MEIS2, FOXA1, RBFOX2, PBX2, NFIC, ZBTB44, ZNF322, IKZF3, ZNF189, SMARCE1, TEAD1, TRIM28, ZNF557, ESR1, CTCF, TCF12, BAF155, EP300, KLF1, MNT, DPF2, SOX6, DDX20, TEAD4, PDX1, EED, POU5F1, ZNF317, ZBTB17, STAT1, NBN, ARID3A, ERG, ZNF341, MYC, SMARCA4, ARID1B, GRHL3, NKX2-1, FOXK2, GABPA, NKX3-1, IKZF1, RCOR1, NFE2, ARNTL, VDR, NR3C1, CEBPB, KMT2A, TRPS1, ZNF257, HDAC2, GATA2, NFIL3, ZNF554, CC2D1A, RUNX1, HDAC1, LDB1, CEBPA, SIN3A, ZFX, PRDM10, ZNF384, OSR2, ZNF184, ARNT, HMBOX1, ZEB2, CBFA2T3, SUPT5H, PML, TERF1, CEBPD, MYB, ZMYM3, PIAS1, C11orf30, STAT5A, RBM22, NUP98-HOXA9, BCL11A, MAFK, ZBTB7A, RBM25, HOXA9, PHIP, BCOR, FOXP1, PRDM6, CBFA2T2, CBX3, MTA3, CREM, FOXA2, PAF1, ZNF600, FOXF1, ZBTB33, CDK9, HOXB13, KDM1A, YY1, NEUROD1, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, TLE3, CEBPG, GFI1B, NR2F2, NR2F1, TCF7L2, PKNOX1, ELF3, BHLHE40, AR, ZBTB42, RNF2, NCOR1, JUND, BRD4, ILF3, ZNF24, ZNF316

Target gene symbol (double-evidenced CRMs): TIAM1,SCAF4,CFAP298,CFAP298-TCP10L,SYNJ1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000265590, ENSG00000159079, ENSG00000159082,

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Deatailed information for cohesin site CDBP00416708