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Basic information

CohesinDB ID: CDBP00416710

Locus: chr21-31725854-31726651

Data sourse: GSE67783, GSE86191, GSE206145-NatGen2015, GSE62063, ENCSR153HNT

Cell type: Fibroblast, HCT-116, K-562, HSPC, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: NIPBL,SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 61%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CBX5, SOX2, MEIS2, FOXA1, RBFOX2, PBX2, LEO1, ZNF28, HDGF, ATF3, ZBTB44, PRDM1, RUNX3, ZNF629, MAF, TRIM28, ZNF557, ZNF121, CTCF, DPF2, PRDM4, IRF4, GATAD2A, EED, GLIS1, POU2F2, ZSCAN5D, TOP2A, ZNF317, ZBTB17, ZBTB48, ZNF563, PBX1, ZNF341, MYC, ZNF2, NKX2-1, BATF3, ZNF667, CEBPB, STAT5B, ZBTB11, CEBPA, ZFX, ZNF770, ZNF18, ZNF35, ZNF384, GATA4, OSR2, ATF2, PBX3, SUPT5H, TEAD3, PML, ZNF558, MYB, EVI1, RBM22, NUP98-HOXA9, SP1, BCL11A, MAFK, HNF4A, ATF7, HOXA9, PHIP, PRDM6, FOXA2, PAF1, ZNF600, ZSCAN16, WT1, ZBTB33, CDK9, HOXB13, NEUROD1, JUNB, OTX2, BATF, TAL1, AGO2, SP7, PKNOX1, AR, ZNF324, BRD4, MAZ, ZNF440, AHR

Target gene symbol (double-evidenced CRMs): PAXBP1,CFAP298-TCP10L,TIAM1,MIS18A,SCAF4,HUNK,SYNJ1,CFAP298

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086,

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Deatailed information for cohesin site CDBP00416710