Browse_each

Basic information

CohesinDB ID: CDBP00416711

Locus: chr21-31727461-31727835

Data sourse: GSE67783, ENCSR153HNT, GSE72082

Cell type: K-562, HSPC, Hep-G2

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 60%, "7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, FOXA1, RXRB, KDM3A, HDGF, MEN1, THAP1, ZBTB44, IKZF3, MORC2, PAX5, SFPQ, TEAD1, ZNF121, LMO2, OCA2, MED26, PITX3, HDAC8, ZNF561, ZNF577, ARID5B, E4F1, SOX5, PAX8, E2F4, ZNF674, ZNF528, KMT2B, GATAD2A, JARID2, NANOG, POU5F1, ZNF263, BRD3, CTBP1, ZMYND11, ERF, DUX4, STAT1, ZNF134, SAP130, ERG, ZBTB8A, EZH1, SMARCA4, RFX1, TOP1, FOXK2, UBN1, RCOR1, NR2F6, NFRKB, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, ZNF257, KLF17, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, NR2C2, HCFC1, ZNF785, RELB, HCFC1R1, EP400, RUVBL2, RUNX1, HDAC1, CEBPA, NKX2-2, IRF3, SP5, TRIM22, SMARCC1, PRDM10, ZNF549, ZBTB2, TFDP1, ELK1, ATF2, FOXM1, SP2, SMARCB1, GMEB1, TERF1, PML, PIAS1, SMAD1, C11orf30, EVI1, STAT5A, GSPT2, ARID2, IKZF5, ZSCAN31, AFF1, MBD2, ELL2, HMGB1, ETV4, NFATC3, MEF2B, CBX3, ZNF207, CREM, CHD2, PAF1, NFATC1, SS18, ZSCAN16, WT1, MEF2C, CREB3L1, NEUROD1, TCF4, ZFP36, BATF, MAF1, SPIB, PLAG1, KLF4, BCL11B, ZFP69B, ZBTB6, MED, EGR2, ELF3, RBM14, ARID4B, RXR, EGLN2, ZNF366, ZBTB26, HSF1, NCOR1, SCRT1, ILF3, ZNF316, FOSL1, ZNF660, XBP1, KDM4B, SRSF4, PBX2, ZNF596, HNRNPK, ATF3, ZFP64, HNRNPUL1, RUNX3, CBFB, TP63, ZSCAN4, MITF, ZNF467, MAF, JMJD1C, INTS11, ELF1, MYOG, RBM39, SNAI2, KLF10, SMAD5, FUS, CTCF, TAF3, JUN, ZBTB20, MNT, LMO1, DPF2, RYBP, IRF4, PDX1, TFAP2C, MLX, RBPJ, ZSCAN21, ZBTB17, ZBTB48, MTA2, NONO, SRF, DDX5, NBN, PBX1, ONECUT1, KDM4A, HOMEZ, FOXP2, ZNF2, RXRA, NKX3-1, PRDM14, LEF1, MIER3, HNRNPH1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, ZKSCAN5, KDM5A, ZBTB14, ZNF146, ZSCAN29, SMARCA5, NFIL3, THAP11, ZNF585A, EZH2phosphoT487, SOX13, AFF4, POU4F2, ZNF770, ZMIZ1, ZNF18, SP3, ARNT, BACH1, ZNF48, PRDM9, HMBOX1, ZEB2, NFYA, NCAPH2, MAFB, ZNF10, HMGXB4, TEAD3, ZXDB, U2AF1, TAF7, KLF9, TBX5, USF1, SP1, BCL11A, TFAP2A, ATF7, SALL4, ASH2L, CTBP2, GLIS2, PRDM6, SMC3, MLLT1, STAG1, STAG2, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MAFF, ESR2, ZNF580, ZKSCAN1, BCL3, KDM1A, KAT2B, BRG1, ZIC2, PCGF1, GATA3, KLF15, TAL1, NRIP1, ZNF143, AGO2, MTA1, TP53, NFKB1, ZSCAN22, BRD2, PHF5A, KAT8, TBX21, EGR1, RB1, TFIIIC, RNF2, BRD4, SPIN1, JUND, CUX1, ZSCAN23, ZNF468, PGR, CBX5, FANCL, SOX2, PATZ1, LEO1, UBTF, RING1B, TFAP4, SIN3B, CHD7, ATF4, MXD4, ZNF189, SMARCE1, MZF1, KLF6, NFE2L2, SAP30, ESR1, ZNF217, KLF1, ZNF695, SOX9, SOX4, E2F6, TRIM24, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ZSCAN5A, ZMYND8, ERG2, SP4, TBP, HNF4G, HOXC5, OGG1, SMARCC2, ETS1, MYC, ARID1B, KLF12, NKX2-1, MCRS1, GABPA, STAT3, IKZF1, INO80, DNMT3B, SRSF3, EZH2, ZNF652, PHF8, SPI1, ZNF202, PCBP1, HDAC2, INTS13, GATAD2B, NFYB, ZNF76, NCOA2, ZNF554, ETV5, BCL6, SIN3A, ERG3, RARA, NFYC, CREBBP, ZNF35, TAF15, ZNF384, SMAD4, CBFA2T3, CDK8, CSNK2A1, ZEB1, NCOA1, SREBF2, RBM22, MAFK, HNF4A, NR4A1, REST, ARID1A, ZHX1, HOXA9, HNRNPLL, BCOR, FOXP1, AATF, NCOR2, CXXC4, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, ZNF30, JDP2, ZNF574, ZNF823, YY2, FOXO3, ZNF318, RELA, TARDBP, ZNF282, SKIL, MGA, MAX, ZNF223, ZNF592, GFI1B, NEUROG2, NR2F1, KDM5B, TCF7L2, PKNOX1, MYOD1, T, AR, KMT2D, ZNF324, HEXIM1, DMAP1, AHR, FOSL2, ZNF391, HMG20A, ZSCAN5C, HMGN3, MEIS2, SUZ12, RBFOX2, ZNF28, ZFHX2, SFMBT1, INSM2, NFIC, ZNF362, CTCFL, PRDM1, KLF14, MECOM, CDX2, ZNF629, THRAP3, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, USF2, TCF12, BAF155, EP300, GATA6, GLI4, SOX6, CREB3, ZNF512B, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, BRD1, MYCN, RUNX1T1, ID3, CDK7, GATAD1, GMEB2, ARID3A, ZNF585B, MIER1, ZNF341, RAD21, GRHL3, APC, ZNF614, XRCC5, NFE2, ZNF639, JMJD6, FEZF1, ZNF664, TFE3, HBP1, IRF1, EHF, ZGPAT, MRTFB, MYF5, ATF1, PTBP1, SMC1A, CBX1, SIRT6, ZNF335, ZFX, ZNF534, FIP1L1, SMAD3, PCBP2, NMYC, TWIST1, PRPF4, NOTCH1, BRD9, RUNX2, CDK6, GATA4, OSR2, ZNF184, ZSCAN30, NRF1, NR2C1, SUPT5H, CHD1, FOS, MED1, CEBPD, MYB, SCRT2, KDM6B, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NUP98-HOXA9, NIPBL, ZBTB7A, CCNT2, PHIP, TCF3, ZNF783, SKI, NELFA, KLF13, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBED1, FOXF1, ZBTB33, CDK9, HOXB13, YY1, ZNF148, ASXL1, BRCA1, SP140, HIF1A, OTX2, ZNF519, ZNF740, ZNF449, GATA1, HAND2, TLE3, CEBPG, SP7, NCOA3, NR2F2, ZNF687, ZNF213, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, MYNN, NOTCH3, CLOCK, MAZ, ZNF24

Target gene symbol (double-evidenced CRMs): TIAM1,SYNJ1,CFAP298,CFAP298-TCP10L,SCAF4,MIS18A,PAXBP1,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086,

eachgene

Deatailed information for cohesin site CDBP00416711