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Basic information

CohesinDB ID: CDBP00416715

Locus: chr21-31737021-31738863

Data sourse: GSE132649, GSE206145-NatGen2015, ENCSR153HNT, GSE73207

Cell type: K-562, T-47D, Fibroblast, TF-1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 83%, "7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, HMGN3, NME2, MEIS2, FOXA1, PBX2, MLL4, HDGF, ATF3, NFIC, PRDM1, IKZF3, ATF4, SMARCE1, MITF, HDAC3, CDC5L, TRIM28, NFE2L2, USF2, ZFP91, JUN, TCF12, EP300, E4F1, KLF1, MNT, PYGO2, DPF2, PAX8, TRIM24, ZNF407, SOX6, TEAD4, GTF2F1, EED, ID3, CTBP1, MTA2, STAT1, NBN, ARID3A, PHB2, TBP, MIER1, SMARCC2, MYC, SMARCA4, ARID1B, NKX2-1, FOXK2, IKZF1, RCOR1, LEF1, NR2F6, NFE2, NR3C1, CEBPB, KMT2A, TBL1XR1, ELF4, SPI1, HDAC2, GATA2, ZNF644, GATAD2B, ZSCAN29, FLI1, MXI1, SMARCA5, RELB, EP400, CC2D1A, MAFG, HDAC1, LDB1, ZFX, ZNF770, ZMIZ1, SMARCC1, ZBTB2, ZNF384, IRF2, BRD9, RUNX2, ZNF184, PBX4, ARNT, PRDM9, ZEB2, HMBOX1, CBFA2T3, FOXM1, FOS, SMARCB1, MED1, GMEB1, PML, CEBPD, ZMYM3, SMAD1, C11orf30, L3MBTL2, NCOA1, STAT5A, KLF16, MAFK, BCL11A, NR4A1, REST, ZBTB7A, CCNT2, ATF7, AFF1, BCOR, MBD2, STAT2, MLLT1, NFATC3, CBFA2T2, FOXA2, MTA3, EBF1, CBX3, CREM, CHD2, ZNF600, ZSCAN16, MAFF, ZKSCAN1, KDM1A, RELA, NEUROD1, CHAMP1, ZFP36, GATA3, TAL1, MAX, ZNF143, MTA1, GATA1, ZNF592, NR2F2, ZKSCAN8, NR2F1, TP53, PKNOX1, BHLHE40, AR, ZBTB40, NCOR1, RNF2, JUND, BRD4, MAZ, ZNF24, ADNP, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): MIS18A,PAXBP1,TIAM1,HUNK,SCAF4,CFAP298-TCP10L,SYNJ1,CFAP298

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000265590, ENSG00000159079, ENSG00000159082, ENSG00000159086,

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Deatailed information for cohesin site CDBP00416715