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Basic information

CohesinDB ID: CDBP00416720

Locus: chr21-31752382-31752744

Data sourse: GSE206145-NatGen2015, GSE68388

Cell type: Fibroblast, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 71% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 86%, "7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, MEIS2, NME2, XBP1, FOXA1, PBX2, ATF3, NFIC, ZNF189, ELF1, TEAD1, SNAI2, NFE2L2, ESR1, PITX3, JUN, TCF12, CTCF, EP300, ZNF157, DPF2, ZNF350, TEAD4, ZSCAN5D, ZNF263, MYCN, DUX4, ZSCAN5A, MYC, SMARCA4, ARID1B, GRHL3, NKX2-1, GABPA, STAT3, RCOR1, NFE2, NR3C1, CEBPB, GRHL2, EBF3, GATA2, RUNX1, MAFG, CEBPA, SIN3A, ZFX, SMAD3, TWIST1, RUNX2, CDK6, ZNF184, ARNT, DAXX, PBX4, HMBOX1, PBX3, CBFA2T3, FOS, CDK8, C11orf30, REST, ARID1A, ZNF479, SMC3, CBFA2T2, CHD2, GTF2B, BCL3, KDM1A, YY1, JUNB, ISL1, HIF1A, GATA3, GATA1, HAND2, NCOA3, TP53, PHOX2B, AR, MAML3, BRD4, JUND, TBX2, ZNF24, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): HUNK,MIS18A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159055,

eachgene

Deatailed information for cohesin site CDBP00416720