- Basic information
- CohesinDB ID: CDBP00416721
- Locus: chr21-31753017-31753300
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Data sourse: GSE206145-NatGen2015, ENCSR000EHX
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Cell type: Fibroblast, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 87%,
"14_ReprPCWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, MEIS2, NME2, XBP1, FOXA1, PBX2, ATF3, NFIC, ZNF189, ELF1, TEAD1, SNAI2, NFE2L2, ESR1, PITX3, JUN, TCF12, CTCF, EP300, ZNF157, DPF2, ZNF350, TEAD4, ZSCAN5D, ZNF263, MYCN, DUX4, ZSCAN5A, MYC, SMARCA4, ARID1B, GRHL3, NKX2-1, GABPA, STAT3, RCOR1, NFE2, NR3C1, CEBPB, GRHL2, EBF3, GATA2, RUNX1, MAFG, CEBPA, SIN3A, ZFX, SMAD3, TWIST1, RUNX2, CDK6, ZNF184, ARNT, DAXX, PBX4, HMBOX1, PBX3, CBFA2T3, FOS, CDK8, C11orf30, REST, ARID1A, ZNF479, SMC3, CBFA2T2, CHD2, GTF2B, BCL3, KDM1A, YY1, JUNB, ISL1, HIF1A, GATA3, GATA1, HAND2, NCOA3, TP53, PHOX2B, AR, MAML3, BRD4, JUND, TBX2, ZNF24, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): MIS18A,HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
- Related loop:
chr21:31250000-31275000~~chr21:31725000-31750000,
chr21:31725000-31750000~~chr21:31850000-31875000,
chr21:31725000-31750000~~chr21:31950000-31975000,
chr21:31725000-31750000~~chr21:32250000-32275000,
chr21:31725000-31750000~~chr21:32575000-32600000,
chr21:31725000-31750000~~chr21:32600000-32625000,
chr21:31725000-31750000~~chr21:32750000-32775000,
chr21:31725000-31750000~~chr21:36975000-37000000,
chr21:31750000-31775000~~chr21:31850000-31875000,
chr21:31750000-31775000~~chr21:31950000-31975000,
chr21:31750000-31775000~~chr21:32250000-32275000,