- Basic information
- CohesinDB ID: CDBP00416732
- Locus: chr21-31780386-31782267
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, ENCSR760NPX, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE25021, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE93080, GSE138405, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE138105, GSE145327, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR807WAC, ENCSR495WGO, ENCSR981FDC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE55407, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE62063, ENCSR944ZCT, GSE110061, GSE129526, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS
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Cell type: RH4, GM2610, SLK, GM19240, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, HeLa-Tet-On, GM19193, THP-1, GM19099, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, Neurons-H1, A-549, GM19238, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 42% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.478
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF22, ZNF362, ZNF384, DDX5
- Target gene symbol (double-evidenced CRMs): CFAP298-TCP10L,HUNK,MIS18A,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
- Related loop:
chr21:10425000-10450000~~chr21:31775000-31800000,
chr21:31623232-31624461~~chr21:31785309-31786753,
chr21:31775000-31800000~~chr21:31875000-31900000,
chr21:31775000-31800000~~chr21:31950000-31975000,
chr21:31775000-31800000~~chr21:32175000-32200000,
chr21:31775000-31800000~~chr21:32225000-32250000,
chr21:31775000-31800000~~chr21:32250000-32275000,
chr21:31780113-31781908~~chr21:32257425-32259313,
chr21:31780114-31782449~~chr21:31872029-31874883,
chr21:31780114-31782449~~chr21:32099458-32101030,
chr21:31780114-31782449~~chr21:32257201-32259301,
chr21:31780119-31781903~~chr21:32257467-32259276,
chr21:31780122-31781850~~chr21:32257426-32259309,
chr21:31780127-31781738~~chr21:32257453-32259309,
chr21:31780134-31782078~~chr21:32256511-32259378,
chr21:31780142-31781787~~chr21:32257174-32259289,
chr21:31780142-31781815~~chr21:32257381-32259299,
chr21:31780158-31781873~~chr21:32256411-32259438,
chr21:31780165-31781913~~chr21:32099650-32100808,
chr21:31780165-31781913~~chr21:32257185-32259313,
chr21:31780170-31781740~~chr21:32257456-32259286,
chr21:31780176-31781715~~chr21:32257195-32260019,
chr21:31780231-31781818~~chr21:32257685-32259278,
chr21:31780232-31781825~~chr21:32257190-32259329,
chr21:31780232-31781825~~chr21:32599877-32601833,
chr21:31780359-31781760~~chr21:32257354-32259325,
chr21:31780368-31781705~~chr21:32257665-32259284,
chr21:31780374-31781732~~chr21:32257419-32259297,
chr21:31780426-31781750~~chr21:32257414-32259287,
chr21:31780470-31781721~~chr21:32257487-32259412,
chr21:31780493-31781691~~chr21:32257422-32259254,
chr21:31784874-31786970~~chr21:32256543-32259299,
chr21:31784900-31787437~~chr21:32256367-32259995,
chr21:31784954-31787383~~chr21:32256342-32259326,
chr21:31784991-31787044~~chr21:32257192-32259306,
chr21:31784993-31787270~~chr21:32256274-32259275,
chr21:31784993-31787270~~chr21:32327704-32330556,
chr21:31784993-31787270~~chr21:32596625-32598153,
chr21:31784999-31787233~~chr21:32256341-32259331,
chr21:31785031-31787247~~chr21:32256511-32259378,
chr21:31785034-31787230~~chr21:32256411-32259438,
chr21:31785041-31787093~~chr21:32257381-32259299,
chr21:31785050-31787026~~chr21:32257438-32259314,
chr21:31785106-31787360~~chr21:32256462-32259302,
chr21:31785152-31787114~~chr21:32257190-32259329,
chr21:31785185-31787232~~chr21:32257399-32259289,
chr21:31785196-31787413~~chr21:32257174-32259289,
chr21:31785206-31787299~~chr21:32257185-32259313,
chr21:31785212-31787770~~chr21:32257426-32259309,
chr21:31785215-31787339~~chr21:31865526-31867042,
chr21:31785215-31787339~~chr21:32257425-32259313,
chr21:31785218-31787331~~chr21:32256496-32259419,
chr21:31785218-31787331~~chr21:32277768-32279016,
chr21:31785220-31787287~~chr21:32257395-32259361,
chr21:31785240-31787470~~chr21:32257315-32259388,
chr21:31785244-31787333~~chr21:32257487-32259412,
chr21:31785247-31787088~~chr21:32257448-32259319,
chr21:31785255-31787043~~chr21:31872357-31875603,
chr21:31785255-31787043~~chr21:32257456-32259286,
chr21:31785255-31787126~~chr21:32256545-32259247,
chr21:31785270-31788289~~chr21:31865214-31867338,
chr21:31785270-31788289~~chr21:31872029-31874883,
chr21:31785270-31788289~~chr21:32257201-32259301,
chr21:31785274-31787238~~chr21:32257419-32259292,
chr21:31785286-31787343~~chr21:31872323-31873497,
chr21:31785286-31787343~~chr21:32257414-32259264,
chr21:31785300-31786985~~chr21:32257739-32259287,
chr21:31785309-31786753~~chr21:32257402-32259244,
chr21:31785324-31787086~~chr21:32256476-32259292,
chr21:31785340-31787022~~chr21:32257685-32259278,
chr21:31785342-31786777~~chr21:32257453-32259309,
chr21:31785386-31787148~~chr21:32257354-32259325,
chr21:31785419-31786802~~chr21:32257417-32259304,
chr21:31785437-31786931~~chr21:32257431-32259307,
chr21:31785448-31786701~~chr21:32257665-32259284,