- Basic information
- CohesinDB ID: CDBP00416733
- Locus: chr21-31783965-31788184
-
Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE93080, GSE67783, GSE86191, GSE101921, ENCSR806UKK, GSE51234, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, GSE115248, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990
-
Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, B-cell, H9-hESC, GM2630, HMEC, Fibroblast, RPE, HEKn, THP-1, Ishikawa, Kelly, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, CNCCs-H9ESC, GM19193, HeLa-Tet-On, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 71% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.244
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 64%,
"14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CHD8, SMC1A, ZNF239, TOP2A, CREB1, ESR1, ZNF513
- Target gene symbol (double-evidenced CRMs): HUNK,CFAP298-TCP10L,URB1,MIS18A,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 35
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
ENSG00000142207,
ENSG00000265590,
ENSG00000159079,
- Related loop:
chr21:10425000-10450000~~chr21:31775000-31800000,
chr21:31623232-31624461~~chr21:31785309-31786753,
chr21:31775000-31800000~~chr21:31875000-31900000,
chr21:31775000-31800000~~chr21:31950000-31975000,
chr21:31775000-31800000~~chr21:32175000-32200000,
chr21:31775000-31800000~~chr21:32225000-32250000,
chr21:31775000-31800000~~chr21:32250000-32275000,
chr21:31780113-31781908~~chr21:32257425-32259313,
chr21:31780114-31782449~~chr21:31872029-31874883,
chr21:31780114-31782449~~chr21:32099458-32101030,
chr21:31780114-31782449~~chr21:32257201-32259301,
chr21:31780119-31781903~~chr21:32257467-32259276,
chr21:31780122-31781850~~chr21:32257426-32259309,
chr21:31780127-31781738~~chr21:32257453-32259309,
chr21:31780134-31782078~~chr21:32256511-32259378,
chr21:31780142-31781787~~chr21:32257174-32259289,
chr21:31780142-31781815~~chr21:32257381-32259299,
chr21:31780158-31781873~~chr21:32256411-32259438,
chr21:31780165-31781913~~chr21:32099650-32100808,
chr21:31780165-31781913~~chr21:32257185-32259313,
chr21:31780170-31781740~~chr21:32257456-32259286,
chr21:31780176-31781715~~chr21:32257195-32260019,
chr21:31780231-31781818~~chr21:32257685-32259278,
chr21:31780232-31781825~~chr21:32257190-32259329,
chr21:31780232-31781825~~chr21:32599877-32601833,
chr21:31780359-31781760~~chr21:32257354-32259325,
chr21:31780368-31781705~~chr21:32257665-32259284,
chr21:31780374-31781732~~chr21:32257419-32259297,
chr21:31780426-31781750~~chr21:32257414-32259287,
chr21:31780470-31781721~~chr21:32257487-32259412,
chr21:31780493-31781691~~chr21:32257422-32259254,
chr21:31784874-31786970~~chr21:32256543-32259299,
chr21:31784900-31787437~~chr21:32256367-32259995,
chr21:31784954-31787383~~chr21:32256342-32259326,
chr21:31784991-31787044~~chr21:32257192-32259306,
chr21:31784993-31787270~~chr21:32256274-32259275,
chr21:31784993-31787270~~chr21:32327704-32330556,
chr21:31784993-31787270~~chr21:32596625-32598153,
chr21:31784999-31787233~~chr21:32256341-32259331,
chr21:31785031-31787247~~chr21:32256511-32259378,
chr21:31785034-31787230~~chr21:32256411-32259438,
chr21:31785041-31787093~~chr21:32257381-32259299,
chr21:31785050-31787026~~chr21:32257438-32259314,
chr21:31785106-31787360~~chr21:32256462-32259302,
chr21:31785152-31787114~~chr21:32257190-32259329,
chr21:31785185-31787232~~chr21:32257399-32259289,
chr21:31785196-31787413~~chr21:32257174-32259289,
chr21:31785206-31787299~~chr21:32257185-32259313,
chr21:31785212-31787770~~chr21:32257426-32259309,
chr21:31785215-31787339~~chr21:31865526-31867042,
chr21:31785215-31787339~~chr21:32257425-32259313,
chr21:31785218-31787331~~chr21:32256496-32259419,
chr21:31785218-31787331~~chr21:32277768-32279016,
chr21:31785220-31787287~~chr21:32257395-32259361,
chr21:31785240-31787470~~chr21:32257315-32259388,
chr21:31785244-31787333~~chr21:32257487-32259412,
chr21:31785247-31787088~~chr21:32257448-32259319,
chr21:31785255-31787043~~chr21:31872357-31875603,
chr21:31785255-31787043~~chr21:32257456-32259286,
chr21:31785255-31787126~~chr21:32256545-32259247,
chr21:31785270-31788289~~chr21:31865214-31867338,
chr21:31785270-31788289~~chr21:31872029-31874883,
chr21:31785270-31788289~~chr21:32257201-32259301,
chr21:31785274-31787238~~chr21:32257419-32259292,
chr21:31785286-31787343~~chr21:31872323-31873497,
chr21:31785286-31787343~~chr21:32257414-32259264,
chr21:31785300-31786985~~chr21:32257739-32259287,
chr21:31785309-31786753~~chr21:32257402-32259244,
chr21:31785324-31787086~~chr21:32256476-32259292,
chr21:31785340-31787022~~chr21:32257685-32259278,
chr21:31785342-31786777~~chr21:32257453-32259309,
chr21:31785386-31787148~~chr21:32257354-32259325,
chr21:31785419-31786802~~chr21:32257417-32259304,
chr21:31785437-31786931~~chr21:32257431-32259307,
chr21:31785448-31786701~~chr21:32257665-32259284,