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Basic information

CohesinDB ID: CDBP00416744

Locus: chr21-31847336-31847670

Data sourse: GSE206145-GSE177045

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 71% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 66%, "14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NANOG, PGR, MAFG, ZSCAN5D, FOXA2, PPARG, ZFX, NME2, ERF, GTF2B, DUX4, ZSCAN5A, XBP1, FOXA1, ERG3, DDX5, HOXB13, ZKSCAN1, ERG, HOXC5, RELA, ZNF384, OGG1, MYC, RAD21, PRDM1, ARNT, GRHL3, RXRA, OTX2, GATA3, GABPA, STAT3, NKX3-1, ZNF143, NFE2, HDAC3, ARNTL, TLE3, NR3C1, NR2F2, TEAD1, ETV1, PIAS1, CREB1, EZH2, ESR1, GRHL2, ZNF334, MYOD1, CTCF, SP1, BAF155, SPI1, AR, ZNF157, HDAC2, GATA2, ARID1A, ASH2L, NOTCH3, BRD4, CTBP2, FOXP1, ZIM3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): MIS18A,HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159055,

eachgene

Deatailed information for cohesin site CDBP00416744