- Basic information
- CohesinDB ID: CDBP00416752
- Locus: chr21-31869101-31869249
-
Data sourse: GSE120943, GSE98367
-
Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 56%,
"13_ReprPC": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, SS18, ZFX, NME2, ZBTB48, DDX5, SMARCC1, YY1, ZNF384, NEUROD1, MYC, BRG1, GR, RAD21, SP140, ARNT, RXRA, OTX2, GATA3, PRDM9, GABPA, MAX, ZSCAN4, NR3C1, CEBPB, TEAD1, NR2F2, EZH2, ESR1, PITX3, ZNF334, ZNF652, CTCF, EP300, SP1, AR, PAX3-FOXO1, GATA2, SIX2, FLI1, BRD4, MAZ, TEAD4, ETV5
- Target gene symbol (double-evidenced CRMs): HUNK,URB1,SYNJ1,SCAF4,MIS18A,CFAP298-TCP10L,CFAP298,TIAM1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000156299,
ENSG00000156304,
ENSG00000142149,
ENSG00000159055,
ENSG00000142207,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:31200000-31225000~~chr21:31850000-31875000,
chr21:31622589-31624532~~chr21:31873410-31874559,
chr21:31622590-31624578~~chr21:31865202-31867213,
chr21:31725000-31750000~~chr21:31850000-31875000,
chr21:31750000-31775000~~chr21:31850000-31875000,
chr21:31780114-31782449~~chr21:31872029-31874883,
chr21:31785215-31787339~~chr21:31865526-31867042,
chr21:31785255-31787043~~chr21:31872357-31875603,
chr21:31785270-31788289~~chr21:31865214-31867338,
chr21:31785270-31788289~~chr21:31872029-31874883,
chr21:31785286-31787343~~chr21:31872323-31873497,
chr21:31850000-31875000~~chr21:31950000-31975000,
chr21:31850000-31875000~~chr21:31975000-32000000,
chr21:31850000-31875000~~chr21:32050000-32075000,
chr21:31850000-31875000~~chr21:32075000-32100000,
chr21:31850000-31875000~~chr21:32150000-32175000,
chr21:31850000-31875000~~chr21:32250000-32275000,
chr21:31850000-31875000~~chr21:32275000-32300000,
chr21:31850000-31875000~~chr21:32375000-32400000,
chr21:31850000-31875000~~chr21:32575000-32600000,
chr21:31850000-31875000~~chr21:32600000-32625000,
chr21:31865157-31867306~~chr21:32257685-32259278,
chr21:31865168-31867682~~chr21:32142694-32144879,
chr21:31865168-31867682~~chr21:32256342-32259326,
chr21:31865180-31867368~~chr21:32257185-32259313,
chr21:31865190-31867889~~chr21:32075693-32077755,
chr21:31865190-31867889~~chr21:32256367-32259995,
chr21:31865192-31867355~~chr21:32257195-32259363,
chr21:31865195-31867134~~chr21:32257381-32259299,
chr21:31865197-31867074~~chr21:32256511-32259378,
chr21:31865202-31867213~~chr21:32257174-32259289,
chr21:31865202-31867229~~chr21:32257395-32259361,
chr21:31865202-31867229~~chr21:32825802-32827847,
chr21:31865206-31867094~~chr21:32256476-32259292,
chr21:31865207-31867006~~chr21:32256496-32259419,
chr21:31865209-31867146~~chr21:32257476-32259450,
chr21:31865210-31867077~~chr21:32257453-32259309,
chr21:31865211-31867117~~chr21:32257438-32259314,
chr21:31865214-31867338~~chr21:32257201-32259301,
chr21:31865217-31867110~~chr21:32257228-32259294,
chr21:31865220-31867254~~chr21:32256411-32259438,
chr21:31865221-31867042~~chr21:32257414-32259264,
chr21:31865221-31867070~~chr21:32257315-32259388,
chr21:31865222-31867020~~chr21:32257456-32259286,
chr21:31865228-31867355~~chr21:32257190-32259329,
chr21:31865230-31867361~~chr21:32256274-32259275,
chr21:31865232-31867115~~chr21:32257195-32260019,
chr21:31865233-31867108~~chr21:32257487-32259412,
chr21:31865235-31867832~~chr21:32257485-32259289,
chr21:31865244-31867006~~chr21:32257426-32259309,
chr21:31865247-31867652~~chr21:32257419-32259292,
chr21:31865248-31867144~~chr21:32256462-32259302,
chr21:31865248-31867144~~chr21:32598994-32601796,
chr21:31865252-31867066~~chr21:32257486-32259262,
chr21:31865272-31867342~~chr21:32256341-32259331,
chr21:31865272-31867342~~chr21:32599933-32601810,
chr21:31865293-31867052~~chr21:32257402-32259244,
chr21:31865357-31867257~~chr21:32257638-32259280,
chr21:31865428-31867009~~chr21:32257414-32259287,
chr21:31865442-31866981~~chr21:32257354-32259325,
chr21:31865442-31866981~~chr21:32599635-32601835,
chr21:31865450-31867127~~chr21:32257447-32259293,
chr21:31865459-31867029~~chr21:32257757-32259222,
chr21:31865464-31867091~~chr21:32256545-32259247,
chr21:31865464-31867092~~chr21:32257192-32259306,
chr21:31865470-31866930~~chr21:32257417-32259304,
chr21:31865481-31867115~~chr21:32257677-32259293,
chr21:31865496-31866966~~chr21:32257419-32259297,
chr21:31865505-31867043~~chr21:32256543-32259299,
chr21:31865515-31867075~~chr21:32257445-32259345,
chr21:31865537-31866893~~chr21:32257665-32259284,
chr21:31865585-31866840~~chr21:32257379-32259282,
chr21:31865594-31866849~~chr21:32257485-32259262,
chr21:31871809-31875540~~chr21:32256411-32259438,
chr21:31872039-31874494~~chr21:32256511-32259378,
chr21:31872042-31874581~~chr21:32256342-32259326,
chr21:31872118-31875754~~chr21:32256367-32259995,
chr21:31872126-31874557~~chr21:32257195-32259363,
chr21:31872415-31873934~~chr21:32257185-32259313,
chr21:31872509-31873790~~chr21:32257190-32259329,
chr21:31872517-31873744~~chr21:32257476-32259450,
chr21:31872680-31874526~~chr21:32577373-32579026,