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Basic information

CohesinDB ID: CDBP00416754

Locus: chr21-31879191-31880604

Data sourse: ENCSR000BLD, ENCSR000BTU, GSE67783, GSE86191, ENCSR153HNT, GSE83726, GSE116344, GSE25021

Cell type: MCF-7, H1-hESC, HCT-116, RH4, Ishikawa, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 71% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 30%, "15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA1, SUZ12, MLL4, TFAP4, ATF3, NFIC, CDX2, MYOG, SNAI2, ESR1, JUN, TCF12, CTCF, EP300, IRF4, TEAD4, FOXA3, CHD8, MYCN, ZNF263, TOP2A, ZBTB48, STAT1, ERG, MYC, SMARCA4, RAD21, PROX1, STAT3, XRCC5, NR3C1, CEBPB, ZNF750, CREB1, CCAR2, EZH2, FLI1, MYF5, CTNNB1, BCL6, EZH2phosphoT487, ZFX, TET2, SMARCC1, CREBBP, PRPF4, ZNF384, PBX4, SOX11, ZNF48, PRDM9, FOXM1, FOS, MED1, RBM22, SP1, HNF4A, SMC3, STAG1, ZNF394, TBL1X, FOXA2, SS18, WT1, TCF7, CDK9, KDM1A, YY1, RELA, JUNB, NEUROD1, BRG1, SP140, TCF4, HIF1A, OTX2, MAX, ZNF143, NCOA3, TCF7L2, TP53, MYOD1, AR, PAX3-FOXO1, RXR, ZBTB26, NCOR1, BRD4, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): HUNK,MIS18A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142149, ENSG00000159055,

eachgene

Deatailed information for cohesin site CDBP00416754