- Basic information
- CohesinDB ID: CDBP00416755
- Locus: chr21-31880837-31881297
-
Data sourse: GSE116344, GSE86191
-
Cell type: RH4, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 35%,
"15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, FOXA1, SUZ12, MLL4, TFAP4, ATF3, NFIC, CDX2, MYOG, SNAI2, ESR1, JUN, TCF12, CTCF, EP300, IRF4, TEAD4, FOXA3, CHD8, MYCN, ZNF263, TOP2A, ZBTB48, STAT1, ERG, MYC, SMARCA4, RAD21, PROX1, STAT3, XRCC5, NR3C1, CEBPB, ZNF750, CREB1, CCAR2, EZH2, FLI1, MYF5, CTNNB1, BCL6, EZH2phosphoT487, ZFX, TET2, SMARCC1, CREBBP, PRPF4, ZNF384, PBX4, SOX11, ZNF48, PRDM9, FOXM1, FOS, MED1, RBM22, SP1, HNF4A, SMC3, STAG1, ZNF394, TBL1X, FOXA2, SS18, WT1, TCF7, CDK9, KDM1A, YY1, RELA, JUNB, NEUROD1, BRG1, SP140, TCF4, HIF1A, OTX2, MAX, ZNF143, NCOA3, TCF7L2, TP53, MYOD1, AR, PAX3-FOXO1, RXR, ZBTB26, NCOR1, BRD4, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): HUNK,MIS18A
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops