- Basic information
- CohesinDB ID: CDBP00416759
- Locus: chr21-31888931-31889583
-
Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, GSE138405, GSE76893, GSE105028, GSE206145, ENCSR981FDC, ENCSR247LSH, ENCSR000EHX, GSE138105, ENCSR703TNG, GSE116344
-
Cell type: MCF-7, H1-hESC, Hela-Kyoto, RH4, HEK293T, Hep-G2, SLK, A-549, SK-N-SH, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 39%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, SOX2, HNF1A, PATZ1, FOXA1, ATF3, ZFP64, CHD7, PRDM1, ZNF189, ZNF629, ELF1, TEAD1, ETV1, LMO2, ESR1, CTCF, TCF12, BAF155, ZBTB20, GATA6, TEAD4, PDX1, TFAP2C, GLIS1, POU5F1, BRD3, ZNF263, ZSCAN21, ZBTB17, ZBTB48, ERG, ZBTB21, ZBTB8A, RAD21, PROX1, NKX2-1, GABPA, STAT3, RCOR1, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, EZH2, GRHL2, FEZF1, EBF3, TRPS1, ZHX2, SPI1, EHF, GATA2, ELF5, SMC1A, SMAD3, CBX8, SMARCC1, PRDM10, CREBBP, OSR2, ZNF184, GR, ARNT, PBX4, ZNF518A, CHD1, FOS, TEAD3, TERF1, PIAS1, TFAP2A, ARID1A, ASH2L, PHIP, BCOR, PRDM6, ELL2, ZNF394, CBX3, RBBP5, SS18, ZNF600, ZSCAN16, ZNF692, HOXB13, KDM1A, RELA, ISL1, HIF1A, GATA3, ZNF449, SPIB, TP53, PHOX2B, BRD2, ELF3, AR, EGLN2, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): MIS18A,HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 0
- Related genes and loops