- Basic information
- CohesinDB ID: CDBP00416770
- Locus: chr21-31911007-31912130
-
Data sourse: GSE67783, GSE86191, GSE138405, GSE206145-NatGen2015, GSE126990, GSE165895
-
Cell type: Hela-Kyoto, Fibroblast, HCT-116, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 36%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, XBP1, PATZ1, FOXA1, LEO1, MLL4, ZFHX2, THRB, ATF3, CHD7, KLF14, ZNF629, MYOG, TEAD1, TRIM28, NFE2L2, ESR1, OCA2, JUN, CTCF, KLF1, PAX8, E2F1, TEAD4, TFAP2C, GLIS1, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, POU5F1, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZSCAN5A, ERG2, ZBTB21, SMARCA4, TSHZ1, RAD21, GRHL3, NKX2-1, APC, XRCC5, STAT3, RCOR1, ZNF639, ZNF750, NR3C1, CEBPB, CREB1, EZH2, KLF17, GATA2, MXD3, SIX2, PTBP1, RUNX1, ZNF335, ZFX, SIN3A, AFF4, SMAD3, ZNF214, TET2, ERG3, SMARCC1, PRDM10, TWIST1, ZNF18, ZNF133, CDK6, OSR2, ZNF184, PBX4, ARNT, ZNF48, PRDM9, SMAD4, SP2, FOS, SCRT2, ZBTB18, NCOA1, TBX5, RBM22, MAFK, BCL11A, TFAP2A, SP1, ARID2, NKX2-5, ZNF479, HNRNPLL, SMC3, ELL2, STAG1, CBFA2T2, FOXA2, SS18, ZNF600, ZNF692, WT1, YY1, RELA, JUNB, BRG1, ISL1, SP140, ZIC2, MTA1, AGO2, HAND2, ZFP69B, SP7, NR2F1, TP53, MYOD1, EGR2, BRD2, BHLHE40, AR, ZBTB42, ZNF366, ZBTB26, HSF1, BRD4, SCRT1, CLOCK, MAZ, TBX2, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 0
- Related genes and loops