- Basic information
- CohesinDB ID: CDBP00416774
- Locus: chr21-31917222-31917806
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Data sourse: GSE206145-NatGen2015, GSE120943, GSE98367
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Cell type: Fibroblast, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 63%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, NFIA, PGR, CHD8, POU2F2, FOXA2, ZNF263, MYCN, TOP2A, RBPJ, ZFX, SOX13, XBP1, ZNF317, DUX4, WT1, ZBTB48, FOXA1, ZNF506, SRF, DDX5, HOXB13, SMARCC1, KDM1A, YY1, RELA, ERG, ZNF341, OSR2, CTCFL, RAD21, PRDM1, ARNT, HIF1A, ZIC2, KLF14, GATA3, ZNF48, SMC3, MAX, ZSCAN4, XRCC5, ZNF143, PRDM14, MITF, MIER3, PAX5, NR3C1, CEBPB, ZNF750, TEAD3, TEAD1, TRIM28, SP7, CREB1, KLF5, TFAP2C, EZH2, KDM5B, ESR1, TP53, OCA2, FEZF1, ZNF334, SETDB1, TRPS1, PHOX2B, CTCF, EP300, BAF155, TFAP2A, HNF4A, AR, SOX5, SIX2, ZNF777, ZNF548, FOXP1, MAZ, PRDM6, TEAD4, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops