- Basic information
- CohesinDB ID: CDBP00416780
- Locus: chr21-31929569-31930018
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Data sourse: ENCSR167MTG, GSE72082, GSE76893, ENCSR000BLS, ENCSR054FKH, GSE25021, ENCSR000EDW
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Cell type: Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: non-Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 49%,
"5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, SOX2, NME2, HNF1A, XBP1, FOXA1, SUZ12, RXRB, MLL4, ZFHX2, KDM3A, TFAP4, THRB, NFIC, ATF3, ZNF362, CHD7, PRDM1, MXD4, ZSCAN4, ZNF629, TEAD1, ELF1, KLF6, RBM39, KLF10, LMO2, ESR1, RCOR2, TP73, MED26, OCA2, USF2, CTCF, JUN, EP300, MNT, SOX5, RAD51, RFX3, FOXA3, ZNF175, GATAD2A, PDX1, RBPJ, MLX, TFAP2C, JARID2, POU2F2, CHD8, BRD1, ZSCAN5D, ZNF263, MYCN, BRD3, TOP2A, POU5F1, KDM4C, ZBTB17, ZBTB48, ZSCAN5A, DUX4, STAT1, GATAD1, SAP130, ARID3A, HNF4G, ERG, ZNF341, ETS1, SMARCA4, HOMEZ, RAD21, FOXP2, GRHL3, RXRA, NKX2-1, FOXK2, GABPA, STAT3, ZNF614, XRCC5, MIER3, RCOR1, NR2F6, TERF2, HNRNPH1, DNMT3B, NR3C1, CEBPB, ARNTL, CREB1, CCAR2, EZH2, TBL1XR1, BMPR1A, ZNF652, EBF3, GABPB1, ZHX2, ZNF436, SPI1, MIXL1, TFE3, HDAC2, GATA2, SSRP1, ZNF644, MXD3, SIX2, DRAP1, ZGPAT, ZNF766, NFIL3, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, CRY1, SOX13, ZFX, SIN3A, POU4F2, TET2, ERG3, SP5, SMARCC1, PRDM10, MYBL2, RARA, ZNF384, NFYC, PRPF4, CREBBP, GATA4, ZNF184, ARNT, ZNF48, SMAD4, PBX3, FOS, HMGXB4, CDK8, MED1, TEAD3, MYB, SCRT2, U2AF1, ZMYM3, TBX5, MBD1, STAT5A, ZNF22, RBM22, MAFK, SP1, NIPBL, USF1, HNF4A, TFAP2A, BCL11A, IKZF5, REST, ZBTB7A, ASH2L, HNRNPLL, PHIP, TCF3, FOXP1, PRDM6, AATF, SMC3, STAG1, ETV4, ZNF394, SKI, PPARG, FOXA2, TBL1X, CREM, CHD2, NFATC1, ZNF600, ZNF692, MIER2, MAFF, WT1, FOXF1, TCF7, HOXB13, ZKSCAN1, ZNF580, KDM1A, YY1, RELA, FOXO3, BCL3, JUNB, AHR, ISL1, SP140, ZFP36, HIF1A, OTX2, GATA3, TAL1, MAX, ZNF143, HAND2, TLE3, CEBPG, NCOA3, NR2F2, TCF7L2, TP53, ZBTB6, ZNF334, MYOD1, PHOX2B, BRD2, ELF3, PHF5A, KAT8, BHLHE40, AR, ARID4B, NFKBIZ, ZNF324, ZBTB26, HSF1, NOTCH3, BRD4, JUND, SCRT1, CLOCK, CUX1, MAZ, ZSCAN23, DMAP1, FOSL2
- Target gene symbol (double-evidenced CRMs): HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops