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Basic information

CohesinDB ID: CDBP00416785

Locus: chr21-31948121-31948607

Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: non-Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 71% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 47%, "4_Tx": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, PGR, ZNF496, SOX2, XBP1, FOXA1, UBTF, MLL4, HNRNPK, LYL1, ATF3, ZBTB5, CHD7, PRDM1, ZNF189, TP63, ZNF467, JMJD1C, ETV1, LMO2, ESR1, OCA2, CTCF, TCF12, JUN, ARID5B, LMO1, GATA6, KMT2B, ZNF175, PDX1, TFAP2C, NANOG, POU2F2, CHD8, ZSCAN5D, POU5F1, MYCN, TOP2A, CDK7, ZNF263, CTBP1, RUNX1T1, ZBTB17, DUX4, ZBTB48, ERG, HOXC5, OGG1, EZH1, MYC, SMARCA4, RAD21, GRHL3, PROX1, GABPA, STAT3, XRCC5, NKX3-1, IKZF1, RCOR1, DNMT3B, ZNF639, ARNTL, NR3C1, CEBPB, EZH2, PHF8, SPI1, PCBP1, GATA2, MXI1, ZNF766, HCFC1R1, ZIM3, RUNX1, BCL6, CEBPA, EZH2phosphoT487, SIN3A, ZFX, PCBP2, TET2, SMARCC1, PRDM10, ZNF384, NOTCH1, RUNX2, GATA4, ARNT, NRF1, TFDP1, HMGB2, PRDM9, PBX3, FOS, CDK8, MED1, MYB, SCRT2, PIAS1, TAF7, RBM22, USF1, BCL11A, TFAP2A, NIPBL, IKZF5, REST, ZNF479, TCF3, SMC3, NCOR2, STAG1, ZNF283, ZNF316, FOXA2, TBL1X, SS18, ZSCAN16, WT1, FOXF1, TCF7, CDK9, HOXB13, KDM1A, YY1, RELA, NEUROD1, SP140, TCF4, HIF1A, OTX2, GATA3, BHLHE22, TAL1, MAX, SPIB, GATA1, AGO2, KLF4, NEUROG2, TP53, ZNF334, MYOD1, AR, TAF1, ZNF366, EGR1, HSF1, NOTCH3, BRD4, JUND, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): HUNK

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000142149,

eachgene

Deatailed information for cohesin site CDBP00416785