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Basic information

CohesinDB ID: CDBP00416791

Locus: chr21-31973554-31973655

Data sourse: GSE120943, GSE98367

Cell type: Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 71% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 51%, "5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, FOXA1, RUNX3, PRDM1, CHD7, PAX5, MITF, ZNF736, JMJD1C, ELF1, TRIM28, ESR1, USF2, CTCF, TCF12, ARID5B, LMO1, E2F6, RAD51, TFAP2C, GLIS1, NANOG, CHD8, POU5F1, RUNX1T1, CDK7, DUX4, STAT1, ERG, MYC, SMARCA4, RAD21, GRHL3, GABPA, NFE2, VDR, STAT5B, KMT2A, CREB1, EZH2, GRHL2, SPI1, HDAC2, SIX2, FLI1, ZNF766, RELB, RUNX1, EZH2phosphoT487, ZFX, SMAD3, ZNF513, ZNF384, ARNT, PRDM9, CDK8, ZNF264, MYB, ZNF22, MAFK, BCL11A, USF1, NR4A1, TCF3, BCOR, CBFA2T2, RBBP5, MAFF, WT1, MEF2C, HOXB13, KDM1A, RELA, NEUROD1, OTX2, GATA3, TAL1, MAX, PLAG1, TP53, ZNF334, T, TBX21, HSF1, NOTCH3, BRD4, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): AP000311.1,HUNK,SCAF4,TIAM1,ITSN1,MIS18A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 1

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000156299, ENSG00000156304, ENSG00000142149, ENSG00000159055, ENSG00000249209, ENSG00000205726,

eachgene

Deatailed information for cohesin site CDBP00416791