- Basic information
- CohesinDB ID: CDBP00416796
- Locus: chr21-31983009-31983792
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Data sourse: ENCSR000BLD, ENCSR167MTG, ENCSR000EEG, ENCSR230ZWH, GSE67783, GSE72082, GSE138405, GSE86191, ENCSR000BLY, ENCSR000BLS, GSE105028, ENCSR054FKH, ENCSR000EHX, ENCSR635OSG, ENCSR703TNG, GSE25021, GSE116344, ENCSR000EDW, ENCSR917QNE
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, HCT-116, RH4, Hep-G2, SK-N-SH, Liver, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"5_TxWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, EZH2phosphoT487, PGR, SMC1A, POU2F2, HMG20A, CHD8, CEBPA, FOXA2, SOX13, ZFX, ZNF649, XBP1, HNF1A, ZBTB48, WT1, FOXA1, ZBTB33, DDX5, SAP130, HOXB13, ZKSCAN1, ZNF496, ERG, YY1, RELA, CREBBP, ZBTB2, ATF3, AHR, CTCFL, RAD21, GRHL3, RXRA, GATA3, ZNF48, SMAD4, MAX, NRIP1, DACH1, NR2F6, MED1, ZNF736, NR3C1, CEBPB, CEBPG, TEAD3, NR2F2, NCOA3, CEBPD, NR2F1, EZH2, ESR1, PHOX2B, CTCF, ELF3, USF1, SP1, SPI1, RBM22, HNF4A, LMO1, AR, ARID4B, SOX5, BCL11A, REST, JUND, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SYNJ1,HUNK,CFAP298-TCP10L,MIS18A,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:31850000-31875000~~chr21:31975000-32000000,
chr21:31975000-32000000~~chr21:32075000-32100000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32250000-32275000,
chr21:31975000-32000000~~chr21:32600000-32625000,