- Basic information
- CohesinDB ID: CDBP00416798
- Locus: chr21-31986414-31988047
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Data sourse: ENCSR167MTG, GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE105028, GSE206145-NatGen2015, GSE83726, GSE116344, GSE25021
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Cell type: MCF-7, Fibroblast, HCT-116, RH4, Hep-G2, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 43%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, XBP1, PATZ1, FOXA1, ATF3, CTCFL, PRDM1, CBFB, ZNF467, KLF5, TEAD1, KLF6, RBM39, ESR1, OCA2, CTCF, JUN, KLF1, MNT, ZNF512B, TFAP2C, POU2F2, CHD8, ZSCAN5D, MYCN, ZNF263, TOP2A, RUNX1T1, POU5F1, ZBTB17, ZBTB48, ZSCAN5A, STAT1, DDX5, ERG, MYC, ONECUT1, SMARCA4, RAD21, GRHL3, XRCC5, NKX3-1, HNRNPH1, ZNF639, NR3C1, ESRRA, EZH2, KLF8, GRHL2, TRPS1, HDAC2, GATA2, FLI1, NCOA2, RUNX1, SMC1A, EZH2phosphoT487, CRY1, SIN3A, ZFX, TET2, ERG3, ZNF770, SMARCC1, CREBBP, GR, ARNT, FOS, SCRT2, RBM22, TFAP2A, REST, CTBP2, AATF, SMC3, STAG1, TRP47, FOXA2, ZNF600, WT1, HOXB13, YY1, RELA, MCM3, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, AGO2, TLE3, KLF4, NCOA3, NR2F2, ZNF512, NR2F1, ARRB1, AR, PAX3-FOXO1, ZNF366, HSF1, NOTCH3, BRD4, SCRT1, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): SYNJ1,HUNK,CFAP298,MIS18A,CFAP298-TCP10L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:31850000-31875000~~chr21:31975000-32000000,
chr21:31975000-32000000~~chr21:32075000-32100000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32250000-32275000,
chr21:31975000-32000000~~chr21:32600000-32625000,
chr21:31991338-31992891~~chr21:32257485-32259289,
chr21:31991347-31993191~~chr21:32257436-32259286,
chr21:31991417-31992782~~chr21:32257395-32259361,
chr21:31991454-31992738~~chr21:32257485-32259262,
chr21:31991470-31992926~~chr21:32257476-32259450,
chr21:31991525-31992800~~chr21:32256274-32259275,