- Basic information
- CohesinDB ID: CDBP00416802
- Locus: chr21-31993758-31994696
-
Data sourse: GSE67783, ENCSR230ZWH, GSE86191
-
Cell type: Liver, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 46%,
"5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, FOXO1, PGR, SMC1A, BRD1, ZSCAN5D, ZNF263, MYCN, TBL1X, EZH2phosphoT487, ZFX, CTBP1, WT1, SMAD3, ZBTB48, FOXA1, ZSCAN5A, TET2, ERG3, FOXF1, PBX2, ERG2, HOXB13, YY1, RELA, ZBTB2, ZNF90, NFIC, GR, RAD21, SP140, ARNT, NFIB, PAX5, MAX, ZNF143, AGO2, GATA1, CBX2, NR3C1, ESRRA, PDX1, ELF1, ZNF121, TEAD1, SCRT2, ETV1, NR2F2, EZH2, KDM5B, ESR1, EGR2, CTCF, RBM22, BCL11A, SP1, AR, REST, SCRT1, JUND, MAZ, SMC1, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SYNJ1,HUNK,MIS18A,CFAP298-TCP10L,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:31850000-31875000~~chr21:31975000-32000000,
chr21:31975000-32000000~~chr21:32075000-32100000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32250000-32275000,
chr21:31975000-32000000~~chr21:32600000-32625000,
chr21:31991338-31992891~~chr21:32257485-32259289,
chr21:31991347-31993191~~chr21:32257436-32259286,
chr21:31991417-31992782~~chr21:32257395-32259361,
chr21:31991454-31992738~~chr21:32257485-32259262,
chr21:31991470-31992926~~chr21:32257476-32259450,
chr21:31991525-31992800~~chr21:32256274-32259275,