- Basic information
- CohesinDB ID: CDBP00416803
- Locus: chr21-31996734-31997182
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
71% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 49%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, HMG20A, FOXA1, RXRB, TFAP4, CDK2, ATF3, THAP1, MXD4, KLF5, ELF1, TEAD1, RBM39, KLF6, RCOR2, CTCF, EP300, MNT, SOX5, PAX8, E2F6, DMAP1, U2AF2, RFX3, TEAD4, FOXA3, GATAD2A, TFAP2C, RBPJ, MLX, BRD1, ZSCAN5D, MYCN, TOP2A, KDM4C, ZNF778, ZBTB48, ZSCAN5A, DUX4, GATAD1, SAP130, ARID3A, ZNF300, HNF4G, ETS1, SMARCA4, RFX1, HOMEZ, RAD21, GRHL3, XRCC5, ZNF614, PRDM14, MIER3, DNMT3B, HNRNPH1, NR2F6, CEBPB, CREB1, EZH2, EBF3, GABPB1, ZHX2, SPI1, TFE3, HDAC2, GATA2, ZNF644, MXD3, SIX2, DRAP1, MXI1, ZGPAT, NFIL3, ETV5, RUNX1, THAP11, MAFG, BCL6, CEBPA, EZH2phosphoT487, SIRT6, NKX2-2, SOX13, ZFX, SIN3A, TET2, ZNF770, SMARCC1, RARA, ZNF384, ZBTB2, CDK6, NRF1, ARNT, SMAD4, HMGXB4, TEAD3, SCRT2, U2AF1, KLF9, C11orf30, MBD1, ZNF22, RBM22, MAFK, USF1, SP1, HNF4A, IKZF5, ASH2L, FOXP1, STAG1, CBFA2T2, ZNF316, FOXA2, SS18, WT1, MAFF, TCF7, HOXB13, ZNF580, KDM1A, YY1, RELA, NEUROD1, ISL1, SP140, ZIC2, GATA3, MAX, ZNF143, AGO2, HAND2, PLAG1, CEBPG, ZNF334, NFKB1, MYOD1, PHOX2B, ELF3, KAT8, ARID4B, AR, BHLHE40, RXR, HSF1, ZBTB26, SCRT1, BRD4, CUX1, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): HUNK,SYNJ1,CFAP298-TCP10L,MIS18A,CFAP298
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000142149,
ENSG00000159055,
ENSG00000265590,
ENSG00000159079,
ENSG00000159082,
- Related loop:
chr21:27500000-27525000~~chr21:32000000-32025000,
chr21:31850000-31875000~~chr21:31975000-32000000,
chr21:31975000-32000000~~chr21:32075000-32100000,
chr21:31975000-32000000~~chr21:32225000-32250000,
chr21:31975000-32000000~~chr21:32250000-32275000,
chr21:31975000-32000000~~chr21:32600000-32625000,
chr21:31991338-31992891~~chr21:32257485-32259289,
chr21:31991347-31993191~~chr21:32257436-32259286,
chr21:31991417-31992782~~chr21:32257395-32259361,
chr21:31991454-31992738~~chr21:32257485-32259262,
chr21:31991470-31992926~~chr21:32257476-32259450,
chr21:31991525-31992800~~chr21:32256274-32259275,
chr21:32000000-32025000~~chr21:32250000-32275000,