Deatailed information for cohesin site CDBP00416804

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  • Basic information
  • CohesinDB ID: CDBP00416804
  • Locus: chr21-31998160-31999689
  • Data sourse: GSE206145, GSE67783, GSE86191
  • Cell type: RPE, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TES,Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 71% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 41%, "5_TxWk": 27%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, HMG20A, FOXA1, RXRB, TFAP4, CDK2, ATF3, THAP1, MXD4, KLF5, ELF1, TEAD1, RBM39, KLF6, RCOR2, CTCF, EP300, MNT, SOX5, PAX8, E2F6, DMAP1, U2AF2, RFX3, TEAD4, FOXA3, GATAD2A, TFAP2C, RBPJ, MLX, BRD1, ZSCAN5D, MYCN, TOP2A, KDM4C, ZNF778, ZBTB48, ZSCAN5A, DUX4, GATAD1, SAP130, ARID3A, ZNF300, HNF4G, ETS1, SMARCA4, RFX1, HOMEZ, RAD21, GRHL3, XRCC5, ZNF614, PRDM14, MIER3, DNMT3B, HNRNPH1, NR2F6, CEBPB, CREB1, EZH2, EBF3, GABPB1, ZHX2, SPI1, TFE3, HDAC2, GATA2, ZNF644, MXD3, SIX2, DRAP1, MXI1, ZGPAT, NFIL3, ETV5, RUNX1, THAP11, MAFG, BCL6, CEBPA, EZH2phosphoT487, SIRT6, NKX2-2, SOX13, ZFX, SIN3A, TET2, ZNF770, SMARCC1, RARA, ZNF384, ZBTB2, CDK6, NRF1, ARNT, SMAD4, HMGXB4, TEAD3, SCRT2, U2AF1, KLF9, C11orf30, MBD1, ZNF22, RBM22, MAFK, USF1, SP1, HNF4A, IKZF5, ASH2L, FOXP1, STAG1, CBFA2T2, ZNF316, FOXA2, SS18, WT1, MAFF, TCF7, HOXB13, ZNF580, KDM1A, YY1, RELA, NEUROD1, ISL1, SP140, ZIC2, GATA3, MAX, ZNF143, AGO2, HAND2, PLAG1, CEBPG, ZNF334, NFKB1, MYOD1, PHOX2B, ELF3, KAT8, ARID4B, AR, BHLHE40, RXR, HSF1, ZBTB26, SCRT1, BRD4, CUX1, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): HUNK,CFAP298,SYNJ1,MIS18A,CFAP298-TCP10L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 186
  • Number of somatic mutations (non-coding): 186
  • Related genes and loops
  • Related gene: ENSG00000142149, ENSG00000159055, ENSG00000265590, ENSG00000159079, ENSG00000159082,
  • Related loop: chr21:27500000-27525000~~chr21:32000000-32025000, chr21:31850000-31875000~~chr21:31975000-32000000, chr21:31975000-32000000~~chr21:32075000-32100000, chr21:31975000-32000000~~chr21:32225000-32250000, chr21:31975000-32000000~~chr21:32250000-32275000, chr21:31975000-32000000~~chr21:32600000-32625000, chr21:31991347-31993191~~chr21:32257436-32259286, chr21:32000000-32025000~~chr21:32250000-32275000,
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