- Basic information
- CohesinDB ID: CDBP00416806
- Locus: chr21-32006901-32008003
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Data sourse: ENCSR000EFJ, GSE104888, GSE72082, GSE131956, ENCSR000BLS, GSE206145-NatGen2015
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Cell type: Fibroblast, HCT-116, Hep-G2, GBM39, IMR-90
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
66% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 75%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, CHD8, PPARG, EZH2phosphoT487, ZNF660, TOP2A, SS18, ZFX, POU5F1, RBPJ, ZBTB17, SMAD3, SOX2, ZNF770, DDX5, PBX2, MLL4, SMARCC1, RELA, ZNF384, JUNB, ATF3, SMARCA4, ZNF184, CHD7, PRDM1, HIF1A, PROX1, NKX2-1, PRDM9, ZEB2, MAX, PBX3, FOS, ZNF639, MED1, NR3C1, ZNF629, ZNF121, CREB1, ZNF791, TCF7L2, EZH2, TP53, ZNF334, NFKB1, T, TCF12, JUN, NIPBL, BRD2, BHLHE40, ARID2, GATA2, FLI1, BRD4, JUND, E2F1, MRTFB, TEAD4, ZNF554, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): MIS18A,HUNK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops